Aflatoxin, Tau proteins, and vit D receptor

What does the aflatoxin do in the endoplasmic reticulum to cause tau?

Aflatoxin binds the Vit D receptor
https://www.citeab.com/publication/1455664-25483621-toxicity-of-aflatoxin-b1-towards-the-vitamin-d-rece

There are morphological cell shape changes due to microfilament changes and a loss of F-actin with aflatoxin exposure
http://www.ncbi.nlm.nih.gov/pubmed/3111878

aflatoxin poisoning and liver
http://www.ncbi.nlm.nih.gov/pubmed/3111878

ALS and abnormal livers..with bizarre giant mitochondria
http://www.ncbi.nlm.nih.gov/pubmed/3800708

aspergillus infections or trichophyton, pick's disease, ALS, and Asperger's
http://angelabiggs.blogspot.com/2016/03/microtubule-disease-issues-aflotoxin.html

the cytoskeleton and mitochondria
http://www.sciencedirect.com/science/article/pii/S0005272806001101

Tau is a microtubule associated protein
http://www.ncbi.nlm.nih.gov/pubmed/27030133

Tau proteins cover MT during polymerization
http://www.ncbi.nlm.nih.gov/pubmed/26996940

Looks like aflatoxin blocks polymerization ??? which then causes tau to precipitate ?

aflatoxin ends up in the endoplasmic reticulum
https://www.ncbi.nlm.nih.gov/pubmed/12166833

endoplasmic reticulum stresses induces Tau
https://www.ncbi.nlm.nih.gov/pubmed/22101233
https://www.ncbi.nlm.nih.gov/pubmed/26402096

older post
http://angelabiggs.blogspot.com/2016/06/how-is-amyotrophic-lateral-sclerosis.html