Monday, October 17, 2016

Mycobacteria's cGMP and HLA-DR8, Mycobacteria's mitochondrial transcription factor and HLA-B51, then T.gondii and HLA-b35

Are autoimmune diseases associated with HLA-DR8 also associated with mycobacteria?

chron's and HLA-DR8
https://www.jstage.jst.go.jp/article/jcoloproctology1967/51/8/51_8_573/_article

type 2 diabetes and HLA-DR8

http://www.academia.edu/12782187/HLA-DRB1_08_allele_may_help_to_distinguish_between_type_1_diabetes_mellitus_and_type_2_diabetes_mellitus_in_Mexican_children

Psoriasis and HLA-DR8
https://www.ncbi.nlm.nih.gov/pubmed/10733642

Mycobacterias secrete cGMP as it's quorum...does HLA-DR8 bind cGMP?


HLA-B51 links the mycobacterias so something going into the mitochondria

Mycobacteria's ability to increase bcl-2 which blocks mitochondrial triggered apotosis in the host
https://www.ncbi.nlm.nih.gov/pubmed/16172539

What is it that HLA-51 is binding? a mitochondrial transcription factor?


maybe this one?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871555/

are aphthous ulcers due to mitochondrial swelling and apotosis?

I had connected aphthous ulcers with mycobacterias
http://angelabiggs.blogspot.com/2016/02/mycobacterias-and-canker-sores-aphthous.html

Behcets has been known to follow mycobacteria infections
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680530/

HLA-B51 is linked to Behcets
http://onlinelibrary.wiley.com/doi/10.1002/art.24642/full

uclers have been found with Behcets
http://www.behcets.com/site/c.8oIJJRPsGcISF/b.9145375/k.E8A8/Symptoms.htm

brazil found HLA-B35
http://www.sciencedirect.com/science/article/pii/S1808869415306625

note that t.gondii infections are common in Brazil
https://www.ncbi.nlm.nih.gov/pubmed/22776427

which is interesting because i had HLA-B35 connected to schizophrenia's mitochondrial factor

schizophrenia b35
https://www.ncbi.nlm.nih.gov/pubmed/8840390

t.gondii and b35
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810704/pdf/DM33-06-612030.pdf

apoptosis and t.gondii's factor: ROP18
https://www.ncbi.nlm.nih.gov/pubmed/27021182






No comments:

Post a Comment