Does HLA-B8 mean that mitochondrial fission has occurred during an infection?
Several autoimmune diseases have been associated with HLA-B8. Celiac, DH, and graves have been associated with e.coli. Addisons and SJ have been connected to candida infections. (note that graves can be caused by a variety of bacterias)
The connection to HLA-b8 that stands out is hepatitis C. What does this virus have in common with these infections? All of these infections and hepatitis C cause mitochondria fission.
HLA-B8 is a mitochondria mailbox...so does this mailbox signify not just something in the mitochondria of the host but that fact that fisson has occurred?
hepatitis C and hla-b8
http://www.bloodjournal.org/content/91/6/2062?sso-checked=true
hepatitis C and the mitochondria fission
https://www.sciencedaily.com/releases/2014/04/140415143959.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855539/
(hepatitis C goes seems to go to the nucleus using MCR1 so how it causes the fission is not figured out)
e.coli and mitochondria fission
http://onlinelibrary.wiley.com/store/10.1111/febs.12874/asset/febs12874.pdf?v=1&t=iufoc0pg&s=713148a320e8a6deb62f42d9d462d6c9876ce3c5
farsenol induces fragmentation of mitochondria (fission)
http://onlinelibrary.wiley.com/store/10.1111/j.1365-2958.2008.06385.x/asset/j.1365-2958.2008.06385.x.pdf?v=1&t=iufom5mu&s=b71a9ef0e9dea02c279c305f116eabce20a4ec07
Farsenol is a quorum made by candida.
This mitochondrial fission is the only thing I can find connecting these infections with the mitochondria thus explaining the HLA-B8.
Any other ideas?
Several autoimmune diseases have been associated with HLA-B8. Celiac, DH, and graves have been associated with e.coli. Addisons and SJ have been connected to candida infections. (note that graves can be caused by a variety of bacterias)
The connection to HLA-b8 that stands out is hepatitis C. What does this virus have in common with these infections? All of these infections and hepatitis C cause mitochondria fission.
HLA-B8 is a mitochondria mailbox...so does this mailbox signify not just something in the mitochondria of the host but that fact that fisson has occurred?
hepatitis C and hla-b8
http://www.bloodjournal.org/content/91/6/2062?sso-checked=true
hepatitis C and the mitochondria fission
https://www.sciencedaily.com/releases/2014/04/140415143959.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855539/
(hepatitis C goes seems to go to the nucleus using MCR1 so how it causes the fission is not figured out)
e.coli and mitochondria fission
http://onlinelibrary.wiley.com/store/10.1111/febs.12874/asset/febs12874.pdf?v=1&t=iufoc0pg&s=713148a320e8a6deb62f42d9d462d6c9876ce3c5
farsenol induces fragmentation of mitochondria (fission)
http://onlinelibrary.wiley.com/store/10.1111/j.1365-2958.2008.06385.x/asset/j.1365-2958.2008.06385.x.pdf?v=1&t=iufom5mu&s=b71a9ef0e9dea02c279c305f116eabce20a4ec07
Farsenol is a quorum made by candida.
This mitochondrial fission is the only thing I can find connecting these infections with the mitochondria thus explaining the HLA-B8.
Any other ideas?
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