Thursday, October 20, 2016

Amyotrophic lateral sclerosis, HLA-c, the endoplasmic reticulum, the vit D receptor, and an aflatoxin-like compound


Is ALS triggered by aflatoxin like compounds and tau is produced? Previous post I am building on.
http://angelabiggs.blogspot.com/2016/05/amyotrophic-lateral-sclerosis-and.html

Trichophyton cencetricum and ALS...definitely connected but is autoimmune cross-targeting with herpes or is it from the aflatoxin like compound that is made that destroys the nerve?

Aflatoxin like compounds are made by some dermatophytes
http://www.ncbi.nlm.nih.gov/pubmed/1170494
specifically T.concetricum

Guam has high rates of ALS
https://gerontologist.oxfordjournals.org/content/early/2014/07/25/geront.gnu072.full.pdf

High rates of trichophyton concentricum on Solomon children (close to guam and makes you wonder if both areas share this infection)
https://www.researchgate.net/publication/281516255_Trichophyton_concentricum_in_skin_lesions_in_children_from_the_Salomon_Islands

ALS and lakes in new england
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922844/

Has this t.concentricum moved into these lakes?

aflatoxin binds the Vit D receptor
https://www.citeab.com/publication/1455664-25483621-toxicity-of-aflatoxin-b1-towards-the-vitamin-d-rece

ALS is slowed with vit D supplements
https://www.ncbi.nlm.nih.gov/pubmed/24428861

Tau has been found to be reduced with vit D supplementation
http://www.ncbi.nlm.nih.gov/pubmed/24412233


Tau protein as a marker for ALS
https://ftd.med.upenn.edu/uploads/media_items/phosphorylated-tau-candidate-biomarker-for-amyotrophic-lateral-sclerosis.original.pdf

HLA and ALS
https://www.ncbi.nlm.nih.gov/pubmed/7073543

HLA C3 and C4 and als
https://www.ncbi.nlm.nih.gov/pubmed/1347673

aflatoxin and the endoplasmic reticulum

https://books.google.com/books?id=stPNnKYksKkC&pg=PA80&lpg=PA80&dq=aflatoxin+endoplasmic+reticulum&source=bl&ots=-zAWhrU-bX&sig=tzKPpyqsG_m647h0btv40b1hRo4&hl=en&sa=X&ved=0ahUKEwjvib26oOrPAhUJw1QKHYb-BUUQ6AEIQzAH#v=onepage&q=aflatoxin%20endoplasmic%20reticulum&f=false


 HLA-C the mailbox for the endoplasmic reticulum...so is the HLA-C picking up aflatoxin?

aflatoxin uses the vit D receptor like polyomaviruses which then are picked up the HLA-C3 or HLA-C4 depending on which polyomavirus. (maybe the body get confused with aflatoxin and can't decide which virus it is, which it is not, so the immune system uses both?)
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2 comments:

  1. Becky DaleJanuary 20, 2021 at 12:13 PM

    My mom ALS started out with a foot drop on her left foot. From there her left leg lost all muscle tone and all the entire left leg muscles were almost gone. Also her fingers and thumbs "contract" at times. Left arm is losing muscle tone too,she have been suffering from amyotrophic laterals sclerosis (ALS) disease for the last seven years and had constant pain which really get us worried, especially in her knees, the only treatment for this ALS (amyotrophic lateral sclerosis) is natural organic treatments honestly ,Multivitamin Herbal Care has the perfect herbal remedy to Motor Neuron Disease including,getting into bed was also another thing she finds impossible. We had to find a better solution for her condition which has really helped her a lot,The biggest help we had was multivitamincare .org today  (or SMS): +1 -956- 758-7882. They walked us through the proper steps, I highly recommend these herbs to anyone suffering from ALS.

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  2. Vera SMay 24, 2021 at 4:28 AM

    We have to give a try on herbal supplements which effectively get rid of herbal ALS condition dramatically after 15 weeks of her usage,she lost touch with reality. Suspecting it was the medication I took her off the riluzole (with the doctor’s knowledge) and started her on the ALS natural herbal formula we ordered. it is advisable to always try natural herbs at first because multivitamincare. org neutralizes her ALS/MND which surprises everyone at home.

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