Monday, October 10, 2016

Using HLAs to find viral suspects for Alopecia

Looking at HLAs for Alopecia triggers we find too many suspects: 3 types? Do these match with the 3 types of alopecia? Areata, Universalis,  and Totalis

HLA-DQ : Reovirus : Areata Alopecia
HLA-C : Polyomavirus: Universalis Alopecia
HLA-DR : Flu : Totalis Alopecia

Alopecia and HLA-DQ ( mailbox non enveloped  RNA cytosol )
https://www.ncbi.nlm.nih.gov/pubmed/10674369

reovirus and alopecia
http://www.nature.com/nature/journal/v189/n4765/abs/189687a0.html

since POTS might be caused by a reovirus does POTS overlap some alopecia?

celiac disease (which is DQ and reovirus linked) has been connected to alopecia Areata
https://www.ncbi.nlm.nih.gov/pubmed/7557104

Alopecia and HLA-C (mailbox for the ER)
https://www.ncbi.nlm.nih.gov/pubmed/23588886

Polyomaviruses and alopecia
https://www.ncbi.nlm.nih.gov/pubmed/25348766
https://www.ncbi.nlm.nih.gov/pubmed/23593936

Alopecia triggered by hepatitis B vaccine? it is a controversy (hepatitis B is a polyomavirus)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956183/

Earlier post connecting polyomaviruses and vit D receptor

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