Tuesday, March 21, 2017

Attempting to link the demethylation and methylation directly to the viruses (as the orchestrator)

Attempting to link the demethylation and methylation directly to the viruses (as the orchestrator)

breast cancer and DNA methyltransferase 1 (DNMT1)
https://www.ncbi.nlm.nih.gov/pubmed/15755728

DNA methyltransferase expression EBV (herpes) and JC virus (polyomavirus)
https://www.ncbi.nlm.nih.gov/pubmed/25341997

Demethylation and TET
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-015-0134-6
https://academic.oup.com/nsr/article/2/3/318/1426818/Oxidative-DNA-demethylation-mediated-by-Tet
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308928/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960967/

Melanoma and TET2 ( ten-eleven translocation methylcytosine dioxygenase)
https://www.ncbi.nlm.nih.gov/pubmed/27102770

HIV, TET, and demethylation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158049/

Zygote - demethylation- Blastocyte- methylation- Epiblast (pluripotent cells)
       awakens Herv K                                Herv H

Epiblast  -demethylation  - PGCs  -  methylation -Fetus
                    Herv E                              Herv W

viruses: Retrovirus / HPV/flavivirus    Herpes/ polyomaviruses
                   demethylation                     methylation
                      Aggressive cancers           Slow cancers


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