Wednesday, July 29, 2015

Parkinson's and the viruses that could cause cross-targeting

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.

Assuming that a mycobacteria or norcardia like infection has already marked the outside of the cell only one virus is then needed to mark the inside of the substantia nigra.

the flu virus and parkinson's has gotten the most attention (uses dopamine receptors)
https://www.michaeljfox.org/foundation/grant-detail.php?grant_id=500

Flaviviruses use melanocortin receptors and can infect the substantia nigra too.

yellow fever and parkinson's
https://news.google.com/newspapers?nid=1928&dat=19810325&id=5C0jAAAAIBAJ&sjid=uGQFAAAAIBAJ&pg=1174,5236962&hl=en

west nile and parkinson's
http://www.nytimes.com/2003/04/01/health/west-nile-symptoms-found-to-be-deceiving.html

Dengue virus and parkinson's
http://www.biomedcentral.com/1471-2334/13/179

Hepatitis C and parkinson's
http://www.medscape.com/viewarticle/856410

My older post about parkinson's
http://angelabiggs.blogspot.com/2015/05/parkinsons-triggers-and-autoimmune.html









No comments:

Post a Comment