Agent orange, the mitochondria, and autoimmune disease?

Agent orange contains 2 herbicides. It was meant to defoliate the leaves of the plants in the area. What the military did not realize was that people would have their nerves absorb the stuff. There seems to be 2 diseases.  The direct damage to the nerves and the the possible triggering of autoimmune diseases of the nerves.


2,4-Dichlorophenoxyacetic acid :  is a form of auxin (synthetic plant hormone) which gets inside of roots and nerves and is then absorbed by the mitochondria.

2,4,5-Trichlorophenoxyacetic acid : another form auxin

Amyloidosis is the high with Agent orange patients
http://www.ncbi.nlm.nih.gov/pubmed/24906069

We see this amyloid with most mitochondrial diseases. The diacytl of popcorn worker's lungs and alzheimer's disease. Alzheimer's which appears in down syndrome mothers more often and has also been associated with herpes viral infections....suggestive of mitochondrial disfunction to me.

Auxin, this agent orange chemical, is involved in the growth inhibition and mitochondrial signalling (chloroplasts)http://www.plantphysiol.org/content/165/3/1233.full

Auxins bind the mitochondria directly causing disfunction
http://www.ncbi.nlm.nih.gov/pubmed/11566291

Previously on this blog the app protein was suggested to be a growth serine protease involved with neuron growth and that the build up of amyloid was a sign of mitochondrial dysfunction (the nerve tip is calling the mitochondria over and over but it isn't coming down the nerve) It is suggestive that auxin has associations with amyloidosis because of an interaction with human mitochondria.

 Destroying the mitochondrias of nerves explains how it destroys the nerves of the legs. (assuming troops walked through it)

How would agent orange also trigger autoimmune disease? 

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.

IF a person already had a larger infection marking the outside of nerve cells then the agent orange auxin stuff would mark the inside replacing the viral infection. (larger infection like staph or mycobacterias that like the shealth of nerves)

This could explain why some people developed MS on top of the horrible nerve damage.
http://forums.webmd.com/3/multiple-sclerosis-exchange/forum/5354