Internal shakes, nerves, and estrogen levels

Estrogen and nerves: Nerves have a beta estrogen receptor that cycles to the mitochondria
This would indicate that estrogen is involved with nerve function.

could women experiencing internal shakes be low on estrogen?

estrogen receptor-beta is relocated to the mitochondria
http://www.pnas.org/content/101/12/4130.full.pdf
http://www.jbc.org/content/284/14/9540.full

estrogen receptor-beta is primarily in the CNS
http://www.ncbi.nlm.nih.gov/pubmed/9419830

estrogen and idopathic parkinson's (looks like parkinson's)
http://www.ncbi.nlm.nih.gov/pubmed/23931933

replacing estrogen improves parkinson's in women
http://www.ncbi.nlm.nih.gov/pubmed/21824799

Estrogen can decrease amyloid deposits
http://www.ncbi.nlm.nih.gov/pubmed/25206683

This makes sense if estrogen effects the mitochondria and encourages it to move.  Amyloid plaques like what we see in Alzheimer's and I have hypothesized to be a sign of mitochondrial damage and lack of mitochondrial movement down the nerves' axial. (see my alzheimer's posts)

too high of an estrogen exposure results in migraine
http://www.uptodate.com/contents/estrogen-associated-migraine
Teenagers as they get their growth spurts tend to develop this.

For women with estrogen levels that are too low could simple grapefruit juice remedy the situation by blocking the breakdown of estrogen and keeping natural estrogen higher for longer?
http://www.ncbi.nlm.nih.gov/pubmed/23859031

Further estrogen replacement therapy improves sleep so levels
http://www.ncbi.nlm.nih.gov/pubmed/9609575
Do estrogen levels typically drop for sleep?