Lung cancer and co carcinogenesis...second look.

Francis Peyton Rous' Co-carcinogenesis hypothesis: that a virus and a carcinogen together cause cancer. (1966 Nobel prize for HPV work)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135410/

My co-carcinogenesis takes his further because carcinogens inhibit polymerases.

What I surmise from his hypothesis:

Cancer occurs because a carcinogen inhibits the viral polymerase better than the human polymerase. When a virus infects the same cell as a carcinogen they interact.  Instead of the virus making what it wants in the host the infected cell is transformed into a cancer cell by the carcinogen. 

Types of lung cancer (can we match a virus to each type?) This may not be so cut and dry.

Non-small cell lung carcinoma

   Squamous    HPV
   Large cell    Flavivirus
   Large cell neuroendocrine    EBV ?
   Adenocarcinoma    adenoviruses? or retroviruses?

Small oat cell lung cancer

small oat cancer and adenovirus group c ?
https://link.springer.com/article/10.1007/BF01240120

herv h and small cell

Squamous cell carcinoma: HPV

HPV and lung cancer
https://www.ncbi.nlm.nih.gov/pubmed/16525675
https://www.sciencedaily.com/releases/2013/04/130410082732.htm

25% of lung cancer HPV
https://www.hindawi.com/journals/jo/2012/750270/

Large cell carcinoma: flaviviruses

Hepatitis C and lung cancer (some flaviviruses can use MCR1 receptors)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876655/

Large cell neuroendocrine carcinoma and EBV
https://www.hindawi.com/journals/cripa/2015/231070/

Adenocarcinoma

Retroviruses and adenocarcinoma
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1002014
https://www.ncbi.nlm.nih.gov/pubmed/24642139

HIV linked with adenocarcinomas of lung
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121163/

Adenocarcinoma of lung with spindle cell component
https://www.ncbi.nlm.nih.gov/pubmed/1471533

previous post....outdated
http://angelabiggs.blogspot.com/2015/10/lung-cancer-and-co-carcinogenesis.html

on previous posts HPV and Hepatitis C were all linked to demethylation and Herv-k/ Herv-E which means all of these are fast aggressive cancers

 methylation and lung cancer ?
https://www.ncbi.nlm.nih.gov/pubmed/17325423
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039813
http://cancerres.aacrjournals.org/content/69/1/243
https://www.ncbi.nlm.nih.gov/pubmed/26449251
https://www.ncbi.nlm.nih.gov/pubmed/26329363
https://www.ncbi.nlm.nih.gov/pubmed/22310466

The endocrine lung carcinoma is a carcinoid tumor of a slow growing cancer.
https://www.cancer.org/cancer/lung-carcinoid-tumor/about/what-is-lung-carcinoid-tumor.html

This fits with the notion that herpes viruses and retroviruses use methylation awakening Herv-w and herv-h.  The slow growing cancer group.