Multiple sclerosis and autoimmune cross-targeting on the myelin

Autoimmune cross-targeting hypothesis

The layering of 2 different infections on one target triggering autoimmune disease.  A viral infection marking the inside of the target then a bacterial, or fungal, or mycobacteria infection marking the outside.

The cross-targeting is occurring on the myelin.
http://www.sciencedirect.com/science/article/pii/S0092867400811071

HHV6 (6th disease aka roseola)  and multiple sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/12717617
http://www.ncbi.nlm.nih.gov/pubmed/12717618

My previous blog post looked at herpes zoster (HHV3) and mycobacterias or staph
http://angelabiggs.blogspot.com/2016/01/multiple-sclerosis-and-seizures.html

herpes zoster was found in brain stem multiple sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/26907823 

note that the oligodendrocytes have been shown to have estrogen receptors specifically ERbeta which cycles to the mitochondria is found in the myelin of the CNS, spinal cord, and brain
http://www.ncbi.nlm.nih.gov/pubmed/14991836

I have been suggesting that herpes viruses use estrogen receptors to enter cells
http://angelabiggs.blogspot.com/2015/07/do-herpes-viruses-use-estrogen.html

mycobacteria and Epstein barr virus in multiple sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/26956729
http://www.ncbi.nlm.nih.gov/pubmed/26453465

Psoriasis has been connected to MS
http://www.ncbi.nlm.nih.gov/pubmed/26352056
http://www.ncbi.nlm.nih.gov/pubmed/27125193
http://www.ncbi.nlm.nih.gov/pubmed/19924503

psoriasis mycobacteria
http://www.ncbi.nlm.nih.gov/pubmed/24050284
http://www.ncbi.nlm.nih.gov/pubmed/18485527

mycobacteria infect schwann cells which produce myelin
http://www.ncbi.nlm.nih.gov/pubmed/20739294
http://www.ncbi.nlm.nih.gov/pubmed/15019586

Note: schwann cells produce the myelin for the peripheral nerves while oligodendrocytes produce the myelin for the central nervous system....the same sort of cells