Is Wegener’s granulomatosis caused by Autoimmune cross-targeting of h.pylori and polyomaviruses?

Autoimmune cross-targeting hypothesis

The layering of 2 different infections on one target triggering autoimmune disease.  A viral infection marking the inside of the target then a bacterial, or fungal, or mycobacteria infection marking the outside.

wegener's vs. churg-strauss (both anca positive) these are similar
http://www.ncbi.nlm.nih.gov/pubmed/2189156

Kawasaki: mycoplasmas  & hepatitis B (and EBV too?): medium blood vessels

Takayasu: mycobacteria & hepatitis B/ polyomaviruses : large blood vessels

Churg-stauss: aspergillus & hepatitis B/ polyomaviruses : small blood vessels

Is Wegener's: polyomaviruses and h.pylori or spirochetes? small blood vessels

worms and churg-stauss? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1004078/

Bell's palsy and wegener's
http://www.ncbi.nlm.nih.gov/pubmed/15124173
http://www.ncbi.nlm.nih.gov/pubmed/11276335
http://www.ncbi.nlm.nih.gov/pubmed/10908974

bell's palsy and spirochetes
http://www.ncbi.nlm.nih.gov/pubmed/2589070Borrelia
http://www.ncbi.nlm.nih.gov/pubmed/1632233 Borrelia
http://www.ncbi.nlm.nih.gov/pubmed/365078 Syphilis
http://www.ncbi.nlm.nih.gov/pubmed/12284236 syphilis
http://www.ncbi.nlm.nih.gov/pubmed/25648561 Leptospira
http://www.ncbi.nlm.nih.gov/pubmed/21613003 Leptospira
http://www.ncbi.nlm.nih.gov/pubmed/15287387 Leptospira

H.pylori is not a spirochete but a relative of campylobacteria. (c. jejune and h.pylori can cause disease...are they similar to spirochetes in some ways?)

H.pylori and Wegener's
http://www.ncbi.nlm.nih.gov/pubmed/19218713

http://jpp.krakow.pl/journal/archive/12_08_s6/pdf/845_12_08_s6_article.pdf

https://www.researchgate.net/publication/24018101_Correlation_between_Helicobacter_pylori_infection_and_pulmonary_Wegener's_granulomacytosis_activity_J_Physiol_Pharmacol

JC virus and wegener's
http://www.ncbi.nlm.nih.gov/pubmed/14563468

BK virus and ANCA associated vasculitis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142761/

Hepatitis B vaccine and Wegener's
http://www.reuters.com/article/dynavax-idUSBNG23616020090209

ANCA Vasculitis review paper
http://www.aafp.org/afp/2002/0415/p1615.html

 Polyomaviruses (JC virus/sv40, BK, hepatitis B) update: use Vit D receptors

serotonin and Vit D are connected
https://mcdb.colorado.edu/courses/4790/Autism.pdf

if vitamin D levels go up because the Vit D receptors are gone then two things can happen:
 a huge increase of serotonin and hypercalcemia

vit D caused hypercalcemia in Wegener's
https://www.ncbi.nlm.nih.gov/pubmed/9146687
https://www.ncbi.nlm.nih.gov/pubmed/8267026

note that cocaine use can cause a condition like Wegener's granulomatosis
http://www.sciencedirect.com/science/article/pii/S0025619611631005

serotonin B1 receptors have been implicated in the pleasure effects of cocaine
https://www.scripps.edu/newsandviews/e_20030929/parsons2.html

splenic infraction caused by the drug triptan (serotonin)
http://www.ncbi.nlm.nih.gov/pubmed/16767537

triptan is a serotonin antagonist that causes vasodilation by acting on serotonin B1
http://www.ncbi.nlm.nih.gov/pubmed/15853772

splenic infractions are seen with Wegener's granulomatosis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389926/
http://www.ncbi.nlm.nih.gov/pubmed/17889260
http://www.ncbi.nlm.nih.gov/pubmed/10852290

odds are the spleen has serotonin B1 receptors too

Splenic infraction after cocaine use
http://annals.org/article.aspx?articleid=704463

serotonin B1 receptors
https://en.wikipedia.org/wiki/5-HT1B_receptor#Tissue_distribution_and_function