Lambert-eaton myasthenic syndrome and autoimmune cross-targeting with asbestos

Autoimmune cross-targeting hypothesis

The layering of 2 different infections on one target triggering autoimmune disease.  A viral infection marking the inside of the target then a bacterial, or fungal, or mycobacteria infection marking the outside.

For Lambert-eaton myasthenic syndrome the autoimmune cross-targeting starts at the lungs with an enterovirus marking the inside of the lung cell and asbestos marking the outside (replacing the large infection as foreign) 

lambert-eaton myasthenic syndrome LEMS: aceytlcholine receptors involved

http://emedicine.medscape.com/article/1170810-overview

Enteroviruses (d68, coxsackie) use Acetlycholine receptors 

Generalized MG (trunk, arms and legs are weak)

Examples of enteroviruses : d68, coxsackie viruses, polio virus, and  echoviruses

polio virus and thymus
http://www.ncbi.nlm.nih.gov/pubmed/20368632

Acetylcholine receptors, thymus and myasthenia gravis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1536815/
http://www.ncbi.nlm.nih.gov/pubmed/182897

40% of LEM have cancer with it

http://emedicine.medscape.com/article/1170810-overview

non polio enterovirus like d68 infects the lungs

http://www.lung.org/about-us/media/press-releases/american-lung-association-Enterovisus-statement.html?referrer=https://www.google.com/

small lung cancer and asbestos

http://www.asbestos.com/cancer/lung-cancer/

Could this be autoimmune cross-targeting of asbestos and an enterovirus in the lungs? Occurring ontop of the cancer???

Does asbestos cling to the voltage gated calcium channels?

asbestos binds sialic acid

http://www.ncbi.nlm.nih.gov/pubmed/6312192

sialic acid binds sodium gated voltage channels

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217074/

does it bind the same way for the calcium channel? Can this trigger the outside part of cross-targeting autoimmunity?

calcium channels of the heart involve sialic acid
http://www.ncbi.nlm.nih.gov/pubmed/2438678
http://www.ncbi.nlm.nih.gov/pubmed/2420406
verapamil a calcium channel blocker appears to work using sialic acid

so while some of the asbestos is inhibiting the viral polymerase causing cancer...some of the asbestos is bound to the outer membrane at the calcium channels through sialic acid?

Asbestos inhibiting polymerases
http://www.ncbi.nlm.nih.gov/pubmed/21543585

Here is the earlier blog post connecting mesothelioma, adenoviruses, and asbestos
http://angelabiggs.blogspot.com/2015/12/mesothelioma-and-co-carcinogenesis.html

note that for the small cell lung carcinoma it is the enteroviruses (maybe i slightly different group of cells infected?)

curcumin inhibits the replication of human enterovirus 71

http://www.sciencedirect.com/science/article/pii/S2211383514000586



Does this work on other enteroviruses?