Are there 2 types of Restless leg syndrome ?

Restless leg syndrome:

Looking at the overlaps with other diseases I suspect 2 types. A p450 variant and a gaba variant.

P450
Low iron causes p450 to be down regulated. Low iron has been known to trigger restless leg syndrome?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882550/

Those with addison's disease and hypothyroid which are possibly triggered by fungal infections like candida which makes farsenol which inhibits p450 could trigger restless leg syndrome similar to low iron.

Here is a link to my previous post about candida, farsenol, and p450.
http://angelabiggs.blogspot.com/2015/12/candidas-quorum-sensing-and-addisons.html

GABA

• Osteoarthritis (degenerative joint disease). About three-quarters of patients with RLS also have 
• osteoarthritis, a common condition affecting older adults.

If this is the case that 3/4 of RSL have osteoarthritis. GHB prescription withdrawal can cause RSL.
Then are we talking about a pituitary issue or gaba issue?

Here is a link to my previous post about fibromyalgia, strentrophomonas, and pituitary tumors:
http://angelabiggs.blogspot.com/2015/11/stenotrophomonas-possible-connection-to.html

Glutamate increased in restless leg
http://www.ncbi.nlm.nih.gov/pubmed/23624560

what are the levels of gaba in restless leg?
https://clinicaltrials.gov/ct2/show/NCT01109537

Is Crushing disease connected to restless leg syndrome?