Wednesday, September 28, 2016

Does the virus that triggers scleroderma also trigger the associated cancers specifically small cell lung cancer? Is it Epstein-barr?

Does the virus that triggers the scleroderma also trigger the associated cancers?

Cancers with Scleroderma: lung, breast, non-melanoma skin, lymphoma
http://www.medscape.com/viewarticle/846109

EBV associated cancers
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887666/
https://www.ncbi.nlm.nih.gov/pubmed/15129648 (lymphomas)

Scleroderma and EBV
https://www.ncbi.nlm.nih.gov/pubmed/8299265

scleroderma: EBV virus and Cryptococcus (autoimmune cross-targeting hypothesis)
http://angelabiggs.blogspot.com/2014/02/is-scleroderma-autoimmune-disease.html

CMV and EBV in breast cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344231/

lung and breast cancer in scleroderma
https://www.ncbi.nlm.nih.gov/pubmed/8457221

adenocarcinoma and ebv
https://www.ncbi.nlm.nih.gov/pubmed/21654679

gastro/ esophogeal cancer nd EBV
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374449/

scleroderma and small cell lung cancer!!! 
http://onlinelibrary.wiley.com/doi/10.1002/jso.2930290109/abstract
https://www.ncbi.nlm.nih.gov/pubmed/2841907
https://www.ncbi.nlm.nih.gov/pubmed/15897643

small lung cancer and gastric cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316115/

Scleroderma and breast cancer
https://www.ncbi.nlm.nih.gov/pubmed/15801071
https://www.ncbi.nlm.nih.gov/pubmed/24103404

Alpha-herpes viruses: Herpes simplex 1, herpes simplex 2,  herpes zoster : Estrogen-beta receptors (nerves and uterine tissue)...these beta receptors cycle to the mitochondria and won't cause cancer?

Beta-herpes viruses: CMV, HHV6, HHV7 :  Estrogen-related receptors (CMV binding confirmed)

Gamma-herpes viruses: EBV, HHV8 : Estrogen-alpha receptors (lymphocytes, breast involved)

estrogen-alpha receptor up regulated in scleroderma ( EBV? )
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825457/

antibodies to estrogen alpha receptors in scleroderma
https://www.ncbi.nlm.nih.gov/pubmed/24058548

estrogen-alpha receptor and non small cell lung cancer
https://www.ncbi.nlm.nih.gov/pubmed/16033821

Estrogen alpha receptor and breast cancer
http://www.ncbi.nlm.nih.gov/pubmed/14973389

EBV infects epithelial cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246291/

EBV in nasopharyngeal carcinoma
https://www.ncbi.nlm.nih.gov/pubmed/9624611

EBV, nasopharyngeal, and burkitt's lymphoma
http://www.pnas.org/content/70/11/3265.full.pdf

Sclerodermas and nasopharyngeal carcinoma
https://www.ncbi.nlm.nih.gov/pubmed/11085820

scleroderma, EBV and lymphoma
https://www.ncbi.nlm.nih.gov/pubmed/10227462

pulmonary lung fibrosis and EBV
http://www.atsjournals.org/doi/full/10.1164/ajrccm.159.4.9807077#.V-xVp5MrKL8

Fibrosis of the lung is common with scleroderma
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340472/



NOTE that other viruses could trigger the autoimmune cross-targeting with cryptococcus











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