Sunday, September 11, 2016

Looking at Charles Richet's life, T.gondii, and hallucinations

Looking at Charles Richet's 1930 discovery of anaphylaxis and then his obsessions with the "sixth sense".

I can't help wonder these things:

France in general has a high infection rate of T.gondii.  This parasite which prefers the host of cats can also infect other mammals including cows, people, and dogs.

T. gondii has strong associations with Schizophrenia which involves hallucinations.  I have been suggesting that schizophrenia could be a cross-targeting autoimmune reaction of T.gondii and another infection in the brain.

During Charles Richet's lifetime the drink Absinthe was popular among the poor.  This worm wood green fairy drink was known to cause hallucinations in a percent of the population.

Richet was trying to explain the ability, the spiritual energy, as real not hallucinations. (was he himself infected?)

What if....this is a huge assumption and leap....what if the percent of the population that had hallucinations to Absinthe had t.gondii infections.

What if the Absinthe goes to the same area of the brain as the t.gondii thus causes the hallucinations similar to schizophrenia ?

Bee sting reactions and schizophrenia patients
http://www.ncbi.nlm.nih.gov/pubmed/5239954

What if the dogs that had fatal bee reactions in Richet's experiment had t.gondii infections too?

a toxin from sea anemone blocks potassium channels like honey bee toxin does.

T.gondii and T. cruzii have potassium channels
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0032264

T.gondii and t.cruzii infections and bee venom
http://www.ncbi.nlm.nih.gov/pubmed/23562368
https://www.researchgate.net/publication/277891898_14_In_vitro_Effects_of_Some_Bee_Products_on_T_gondii_Tachyzoites

I doubt that dogs are exposed to bees as much as bee keepers which currently seem to be the favored bee anaphylaxis allergy explanation now.

Does thujone play are role? Thujone is a compound in absinthe that acts on GABA receptors.  (not a high concentration) But if the number of receptors are increased in a person.

 Schizophrenia patients have increased GABA receptors.
http://www.ncbi.nlm.nih.gov/pubmed/16362364?dopt=Abstract

T.gondii and GABA receptors
http://mbio.asm.org/content/6/6/e01428-15.full
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003051




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