Wednesday, July 13, 2016

Zika virus, Green Tea, Agouti-related peptides, and the ACTH receptor


Green tea and Zika
http://www.contagionlive.com/news/study-reveals-how-green-tea-could-protect-against-zika-virus

What could be happening here is that the agouti-related proteins are competing with the Zika virus for the ACTH receptors.

Zika and ACTH (hypothesis of a previous blog posts)
http://angelabiggs.blogspot.com/2016/01/does-zika-virus-use-melanocortin.html

Gaba and melanocortin system in the hypothalamus
http://www.nature.com/nrendo/journal/v10/n11/fig_tab/nrendo.2014.160_F1.html
This shows how the neuron releases GABA and Agouti-R together but act on different receptors.

EGCG (green tea) and the hippocampus neurogenesis
http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201200035/abstract
Is this the Agouti-R acting on melanocortin receptors in this case?

Green tea increases serotonin which increases the release of GABA and Agouti-related peptide
http://healthyeating.sfgate.com/can-green-tea-boost-serotonin-3386.html

Agouti-relate peptide
https://en.wikipedia.org/wiki/Agouti-related_peptide
Is made and released with GABA in the hypothalamus only Agouti-R acts on the melanocortin 3 and 2 receptors not the GABA receptor

ACTH is the Melanocortin 2 receptor which is responsible for neurogenesis






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