Togaviruses and Flaviviruses relationship to melanocortin receptors (ZIKA)

Togavirus family viruses once included Flaviviruses but differences in the viral sequences causes them to be separated out renamed.

The question is : Do Togaviruses use melanocortin receptors like the flaviviruses ? They are so similar they were lumped together for years.

I have suggested that cancer cells wear the receptor used by the virus that started them.  For melanoma the west nile virus using a melanocortin receptor was being considered.

The Togavirus Semliki Forest virus has been found infect a high percent of melanoma cells
http://www.ncbi.nlm.nih.gov/pubmed/16849565

Is this ironically because togaviruses like flaviviruses use melanocortin receptors? Does this virus have a high infection rate because of the family relation to the virus that started it?

Looking at the flaviviruses and melanocortin receptors

West nile can infect kidney cells...MR3 or MR4?

Dengue can infect thyroid and embryonic cells...MR5 ?

Zika....ACTH which is the MR2 ?

The virus has a strong match with one receptor and a weak match with others receptors in the same  receptor family


If you look at the tissues expressing the receptors and west nile infecting you can see patterns:

 westnile: skin, kidney, prostate, substantia nigra

note that pigments have been found in prostate cells and substantia nigra

there is a type of renal cell carcinoma that has been found containing pigment (kidney cancer cell)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938559/

antivirals and flaviviruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918146/