Monday, March 7, 2016

Thrombosis and infections

This blog post is attempting to sort the types of thrombosis and figure out which one leads to CAPS

Mycoplasmas and Thrombosis (deep vein and pulmonary embolism of lungs)

SLE or rhematoid arthritis and deep vein/ pulmonary
http://www.ncbi.nlm.nih.gov/pubmed/24472157
http://www.ncbi.nlm.nih.gov/pubmed/23926057

Thrombosis and SLE with rheumatoid arthritis, or BeƧhet’s disease
http://www.natfonline.org/media/22695/july09_metjian_ortel.pdf


Mycobacteria and Thrombosis (deep vein/heart)

Thrombosis and type 2 diabetes
http://onlinelibrary.wiley.com/doi/10.1002/pdi.1960160813/abstract

"deep vein thrombosis" and type 2 diabetes
http://www.sciencedirect.com/science/article/pii/S0741521408011877


Strep and thrombosis (surface clotting)

sinus thrombosis and strep
http://www.ncbi.nlm.nih.gov/pubmed/14691601

ovarian vein thrombosis and strep
http://www.medscape.com/viewarticle/405871_4


Campylobacteria/sutterella and Thrombosis

Caps and the back of the brain
http://www.hindawi.com/journals/crihem/2014/704371/

cerebral vein thrombosis and Guillain barre
http://www.ajemjournal.com/article/S0735-6757(08)00748-1/abstract

Gait/guillain barr and the involvement of the brain in thrombosis
http://www.turner-white.com/pdf/hp_jul01_antibody.pdf

note that guillain barre is cross-targeting autoimmunity with a virus (flu or flaviviruses)
http://angelabiggs.blogspot.com/2016/01/is-guillian-barre-caused-by-autoimmune.html



Catastrophic antiphospholipid syndrome
less than one percent develop CAPS
many patients who develop this have lupus...mycoplasmas

Hemolytic anemia has already been linked to mycoplasmas
http://www.ncbi.nlm.nih.gov/pubmed/988873
http://www.ncbi.nlm.nih.gov/pubmed/577971

child started with TMHA and subsequently developed CAPS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495358/

hemolytic anemia and caps
http://www.ncbi.nlm.nih.gov/pubmed/22784445
http://ard.bmj.com/content/63/6/730.full
http://www.sciencedirect.com/science/article/pii/S0049017212001370


ALS and Thrombosis

Venous Thromboembolism and ALS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032202/

Ischemic colitis and ALS
(no blood flow to intestine due to a clot)

I was considering the ALS form of clotting as caused being unable to move...but maybe there is more here.







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