Hypothesis: The area of the infection matches up with the cytokine proliferating the T cells and the TLR they end up expressing.
il-7 is expressed in the stroma of the bone marrow and thymus during T cell develpment
il-7 is necessary for the TCR development
At the thymus a generic TLR is placed on the proliferating T cells
il-2 is expressed by T cells when the TCR recognizes HLA-A or HLA-B which contain viral DNA from mitochondrial or nuclear infections.
il-15 is expressed by T cells when the TCR recognizes the HLA-D or HLA-C of viral infections of the cytosol, the ER, or bacteria.
The T cells proliferating under il-2 will have TCR that bind HLA-A/B even stronger.
il-2 mito/nuclear virus
il-15 cyto/ER virus or bacteria
il-7 generic
il-7 is expressed in the stroma of the bone marrow and thymus during T cell develpment
il-7 is necessary for the TCR development
At the thymus a generic TLR is placed on the proliferating T cells
il-2 is expressed by T cells when the TCR recognizes HLA-A or HLA-B which contain viral DNA from mitochondrial or nuclear infections.
il-15 is expressed by T cells when the TCR recognizes the HLA-D or HLA-C of viral infections of the cytosol, the ER, or bacteria.
The T cells proliferating under il-2 will have TCR that bind HLA-A/B even stronger.
il-2 mito/nuclear virus
il-15 cyto/ER virus or bacteria
il-7 generic
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