Monday, February 19, 2018

Is il-24 a pore for the golgi?

Does il-24 form a pore like il-26, il-22, and il-19?

il-24 does have the long chain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782067/

il-26  the nuclear pore
il-22 the vacuoles pore
il-19 the mitochondria and nucleus pores

Is il-24 the pore for the golgi?

il-24 is localized to the golgi
http://cancerres.aacrjournals.org/content/64/9/2988.long

il-24 and salmonella while stimulating neutrophils
https://www.ncbi.nlm.nih.gov/pubmed/19830736

salmonella infects the golgi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC204495/

tlr3 and il-24
https://www.ncbi.nlm.nih.gov/pubmed/23449395
https://www.nature.com/articles/cdd201315?WT.ec_id=CDD-201306

(previous hypothesis linked tlr3 to the golgi)

il-24 and mycobacteria

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679252/

do mycobacteria hang out in the golgi?

TLR3 and mycobacteria
https://www.ncbi.nlm.nih.gov/pubmed/24462705

What about il-24 and it's ability to stop cancer? How is it functioning here? Leaking the golgi?

golgi and lung cancer
https://www.genengnews.com/gen-news-highlights/targeting-golgi-apparatus-may-help-prevent-lung-cancer-metastasis/81253458

il-24 and lung cancer
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122439

golgi and certain cancers
http://www.cell.com/cancer-cell/pdf/S1535-6108(16)30047-2.pdf


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