Does the tlr2 heterodimer determine the cytokine?

il-20 with mycoplasma and il-23 with chlamydia both trigger tlr2

Possibly different cytokines because tlr2 heterodimers with tlr1 and tlr6

il-20 and RA
https://www.ncbi.nlm.nih.gov/pubmed/28662439

tlr2 and mycoplasmas
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010739

Keratinocytes: tlr2 with il-20 and tlr3 with ifn lambda
https://www.ncbi.nlm.nih.gov/pubmed/18281438

tlr2 and tlr6 with mycoplasma
https://www.ncbi.nlm.nih.gov/pubmed/14706104

il-23 and tlr2
https://arthritis-research.biomedcentral.com/articles/10.1186/ar3780

chlamydia triggers tlr1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266682/

Possible?

il-20 increases ifn gamma which could reflect a damaged ER which is where mycoplamsas nest

il-20 and ifn gamma
https://www.ncbi.nlm.nih.gov/pubmed/16645593

mycobacteria trigger tlr2 with 1/6,  tlr4, and tlr9
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504976/

what are mycobacteria doing????  Mycobacterias move into host cells and sit in the cytosol but they must be disrupting the mitochondria.

tlr9 is the mitochondria dna net

mycobacteria cause cyto. c release from the mito and change it's morphology
https://www.ncbi.nlm.nih.gov/pubmed/14507307