Does HLA-B27 reflect small modifications of the mitochondria's P-glycoproteins by infections ?

HLA-A the nucleus

HLA-B the mitochondria

HLA-C the endoplasmic reticulum

HLA-DR the cytosol (encapsulated virus or foreign protein)

HLA-DQ the cytosol (not an encapsulated virus)

HLA-DP the plasma membrane (immune system cells APCs)

Does HLA-B27 reflect small modifications of the mitochondria's P-glycoproteins by infections ? 

Ankylosing spondylitis and HLA-B27
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079257/
https://www.ncbi.nlm.nih.gov/pubmed/27826329

Ankylosing inflammation regressed by 54% in the etanercept group 
https://www.ncbi.nlm.nih.gov/pubmed/15818694

Etanercept is a TNF inhibitor

Cells exposed to TNF go through Necrosis where mitochondrias are released from cells
http://www.nature.com/cddis/journal/v5/n7/full/cddis2014277a.html

(high TNF and failing human heart)

TNF activates P-glycoprotein
https://www.ncbi.nlm.nih.gov/pubmed/17982267
https://www.ncbi.nlm.nih.gov/pubmed/17132686

P-glycoprotein in mitochondria
https://www.ncbi.nlm.nih.gov/pubmed/22307172

cell fusion involves p-glycoprotein
https://www.ncbi.nlm.nih.gov/pubmed/12960149

Does the fusion of mitochondria involve p-glycoproteins?

Measles HLA-DR1 and HLA-B27

https://www.ncbi.nlm.nih.gov/pubmed/12117677

HLA-B27 and measles fusion protein
https://www.ncbi.nlm.nih.gov/pubmed/7680390

With measles it was found that a fusion glycoprotein was recognized by HLA-B27

So does the use of HLA-B27 mean that these infections have something that disrupts mitochondrial fusion through p-glycoproteins? 

measles and mitochondrial dysfunction
https://www.ncbi.nlm.nih.gov/pubmed/20167981

reactive arthritis (RF negative) and HLA-B27
salmonella, shegella, campylobacteria

Spirochetes and HLA-B27
H.pylori https://www.ncbi.nlm.nih.gov/pubmed/17183194
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403919/
Lyme http://bjo.bmj.com/content/77/8/480.full.pdf

mitochondrial broken into fragments after H.pylori infection
http://gut.bmj.com/content/53/6/805.full

psoriasis, psoriatic arthritis, crohn's,  mycobacterias and HLA-B27

mitochondrial damage after mycobacterial infection
http://www.jimmunol.org/content/169/9/5181.full

Achilles and HLA-b27
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1002212/

Achilles and TNF
https://www.ncbi.nlm.nih.gov/labs/articles/22572155/

Drug resistance and high p-glycoprotein
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975434/

mitochondrial fusion defect and drug resistance
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455774/

HIV alters fission and fusion of the mitochondria
https://www.ncbi.nlm.nih.gov/pubmed/26611103

HIV to AIDS...HLA-B27?
http://www.aidsreviews.com/files/2004_06_2_089-096.pdf

???? HLA-B27 binds aromatic peptides?
https://www.ncbi.nlm.nih.gov/pubmed/8225441?dopt=Abstract