Rheumatoid arthritis as autoimmune cross-targeting on synoviocyte cells of the joint.

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.

The target of Rheumatoid arthritis might be the synoviocyte cells with mycoplasmas marking the outside and EBV marking the inside.

Fibroblast-like synoviocyte, mycoplasmas, and Rheumatoid arthritis
https://en.wikipedia.org/wiki/Fibroblast-like_synoviocyte
http://www.ncbi.nlm.nih.gov/pubmed/26058928
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC500777/
http://vet.sagepub.com/content/15/3/407.full.pdf
http://www.ncbi.nlm.nih.gov/pubmed/685087
http://www.ncbi.nlm.nih.gov/pubmed/18307980
http://www.ncbi.nlm.nih.gov/pubmed/20236320

EBV detected in synoviocyte of Rheumatic patients
http://www.ncbi.nlm.nih.gov/pubmed/10782808
http://www.ncbi.nlm.nih.gov/pubmed/10857780
http://www.ncbi.nlm.nih.gov/pubmed/17625943
http://www.ncbi.nlm.nih.gov/pubmed/15288002 (review)
http://www.ncbi.nlm.nih.gov/pubmed/17625943