Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease. The immune system is instructed to destroy both the inside and the outside of the target.
Polymyositis and Inclusion body myositis: cross-targeting of skeletal musclesAuto-antibodies like Sjogren's which hints of fungal infection
Is Polymyositis a candida like infection cross-targeting with coxsackie B while inclusion body myositis is chytrid cross-targeting with coxsackie?
Polymyositis been triggered by Coxsackie B
http://www.ncbi.nlm.nih.gov/pubmed/18432367
http://www.ncbi.nlm.nih.gov/pubmed/631901
http://www.ncbi.nlm.nih.gov/pubmed/5490731
Polymyositis and other fungal infections like Candida
http://www.ncbi.nlm.nih.gov/pubmed/15818648
Frogs can have inclusion body myositis: virus and chytrid fungus
http://www.ncbi.nlm.nih.gov/pubmed/12423034
The fungus chytrid that kills frogs hides in crayfish
http://phenomena.nationalgeographic.com/2012/12/18/fungus-bd-frog-crayfish-chytrid/
Regions that eat crayfish like Tennesse should have clusters of Inclusion body myositis: do they?
Electrolytes in frogs infected with chytrid were low
http://www.abc.net.au/science/articles/2009/10/23/2720384.htm?site=science/tricks&topic=latest
Polymyositis and low potassium
http://www.ncbi.nlm.nih.gov/pubmed/3430508
Clay eating and myositis
http://www.ncbi.nlm.nih.gov/pubmed/3340881
Pica might be caused by the parathyroid because it was induced in rats
http://www.ncbi.nlm.nih.gov/pubmed/?term=pica+parathyroid
Could Candida be infecting the parathyroid?
parathyroid is connected with autoimmune polyglandular syndrome one which is already associated with candida infections
Dermatomyositis and lichen planus?
http://www.ncbi.nlm.nih.gov/pubmed/25241001
http://www.ncbi.nlm.nih.gov/pubmed/25545122
http://www.ncbi.nlm.nih.gov/pubmed/4754227
Dermatomyositis and sjogren's
http://www.ncbi.nlm.nih.gov/pubmed/26253095
Vitiligo and polymyositis
http://www.ncbi.nlm.nih.gov/pubmed/24383911
http://www.ncbi.nlm.nih.gov/pubmed/2758715
Hashimoto's and polymyositis
http://www.kjim.org/upload/kjim-28-380.pdf
Leishmaniasis and dermatomyositis
http://www.ncbi.nlm.nih.gov/pubmed/8698915
http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(05)63428-9.pdf
http://www.sciencedirect.com/science/article/pii/S1201971210025270
optic neuritis has been known to be triggered in dermatomyosis
http://rheumatology.oxfordjournals.org/content/43/3/391.2.long
Note that Leishmania parasite infects the sheath of the optic nerve
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110707/
Macrophages are a major factor in polymyositis
http://www.ncbi.nlm.nih.gov/pubmed/15266639
chikungunya usually infects macrophages
http://www.jci.org/articles/view/40104
So I guess the outer infection could be fungus or something like Leishmania. The inner infection a virus like coxsackie or chikungunya????
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