In addition to inducing proliferation of keratinocytes could il-20 disrupt the proton gradient of wounds preventing the neutrophils from migrating there.
v-ATPase, voltage gradients and wound healing
file:///Users/angelabiggs/Downloads/The%20Role%20of%20pH%20and%20the%20V-ATPase%20in%20Electric%20Field%20Guided%20Cell%20Migration.pdf
il-20 and wound healing by inhibiting neutrophils
http://iovs.arvojournals.org/article.aspx?articleid=2270261
neutrophils migrate to cathodes
https://www.researchgate.net/figure/Electrical-migration-of-cells-Neutrophils-respond-to-an-electric-field-by-migrating_fig3_23709207
il-20 could be a proton pore for the plasma membrane disrupting the electric field that would attract the neutrophils
why is this possible?
il-26 a cytokine that forms a nuclear pore
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919036/
il-20 family
http://angelabiggs.blogspot.com/2018/02/il-19-is-mitochondrial-pore-il-26-is.html
The il-20 family cytokine receptors are on immune system cells and boarder cells: the fibroblasts, the epithelial cells, and keratinocytes because when you are tearing cells down you want those protective cells built up.
for regular cells il-20 family cytokines are just proton pores popping membranes
il-26 the nuclear membrane
il-19 the mitochondria membrane
il-22 the vacuoles
il-24 the golgi
il-20 the plasma membrane
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