Combined Autoimmune Cross-targeting hypothesis with the 3 Hormone Location hypothesis: could explain some autoimmune diseases

Corrections:  the cytokines have change for the below rxns. il-4 is only with Tfh. INFgamma is with Th1. il-10 is with Tc.

Autoimmune hypotheses: two infections at the same time triggers autoimmunity. The immune system only wants to focus on the viral infection so it stalls the larger infection with IgG4.

In the case of Eosinphila are IgG4 antibodies generated against the eosinophil cationic protein ?

IgG4 and the cationic protein
https://www.ncbi.nlm.nih.gov/pubmed/1692064
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795490/

RA and cationic protein
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576917/

Alopecia has also been connected to fungal infections of the skin which would  involve IGF-1 and IgE with neutrophils called from th17 cells' il-17a and il-33 of the dendritic cells.

HLA-DQ : Reovirus : Areata Alopecia
HLA-C : Polyomavirus: Universalis Alopecia
HLA-DR : Flu : Totalis Alopecia

anti-neutrophils cytosolic antibodies:  IgG4
https://www.tandfonline.com/doi/abs/10.1080/03009740600844738?journalCode=irhe20