Tuesday, November 7, 2017

Follicular dendritic cells, the Fc receptor, and albumin antigen binding

Follicular dendritic cells

Review paper of FDC
https://www.ncbi.nlm.nih.gov/pubmed/12163300

Albumin and IgG: the Fc receptor binds both
https://www.frontiersin.org/articles/10.3389/fimmu.2014.00682/full

Fc receptors on Follicular dendritic cells
https://www.ncbi.nlm.nih.gov/pubmed/10843680
https://www.ncbi.nlm.nih.gov/pubmed/14634109

HIV infects FDC cells
https://www.ncbi.nlm.nih.gov/pubmed/12163303

HIV is a retrovirus. Retroviruses infect using LH/albumin binding receptors (my hypothesis). Could HIV infect using the Fc receptors?
http://angelabiggs.blogspot.com/2017/03/albumin-binding-receptors-and.html

human serum albumin alone binds bacterial products
http://www.sciencedirect.com/science/article/pii/S0168827814002657

albumin and the immune system
http://www.scopemed.org/?mno=10124


FDC have high levels of C3 complement receptors and they display the antigen carried by them or from antibodies taken in by Fc receptors.

Could FDC also be taking in albumin with antigens bound to them using the Fc receptor?

TNF alpha increased plasma albumin
https://www.ncbi.nlm.nih.gov/pubmed/9513905

peyer's patches removed caused higher albumin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1554968/

the lymph fluid contains albumin as well...think of albumin as an protein sponge collecting things

How do follicular dendritic cells collect antigens for display? Can FDC collect antigens from albumin?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023135/

No comments:

Post a Comment