Thursday, February 27, 2014

Alzheimer's puzzle: Is the mitochondria damaged by herpes or diacetyl and does this cause amyloid plagues? in the lungs or the brain?

This post specific is not focused on an autoimmune disease but Alzheimer's.  I am looking at the  notion of amyloid plaques and the mitochondria.  A continuation of the the Alzheimer's and parkinson's posts. Where it is the destruction of the mitochondria that is key to the development of the diseases.

amyloidosis and the mitochondria (genetic)
http://www.ncbi.nlm.nih.gov/pubmed/19018796
http://www.nature.com/ejhg/journal/v18/n8/full/ejhg201036a.html

amyloidosis and mycobacteria
http://www.deepdyve.com/lp/elsevier/reactive-amyloidosis-in-a-patient-with-mycobacterium-simiae-pulmonary-XcACtyHSzn
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC459761/

type 2 diabetes and mycobacteria
http://www.sciencedirect.com/science/article/pii/S0306987705002045

amyloidosis, Karposi's, and herpes (non genetic)
http://www.ncbi.nlm.nih.gov/pubmed/10842716
http://www.ncbi.nlm.nih.gov/pubmed/498024 
herpes virus 8 with karposi? Alzheimer's is connected to herpes virus 1

Herpes destroys host's mitochondrial DNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796774/
the herpes virus drives the mitochondria down the nerve root to other nerves!
http://www.sciencedirect.com/science/article/pii/S1931312812001047 
herpes causes amyloid
http://www.ncbi.nlm.nih.gov/pubmed/17980964
http://www.ncbi.nlm.nih.gov/pubmed/16109164
 
 Herpes and Alzheimer's Patients
http://www.ncbi.nlm.nih.gov/pubmed/18973185
http://www.ncbi.nlm.nih.gov/pubmed/22216291
http://www.ncbi.nlm.nih.gov/pubmed/18982063
http://www.ncbi.nlm.nih.gov/pubmed/23261465


in Cardiac tissue? similar to nerves?
http://www.ncbi.nlm.nih.gov/pubmed/24182678 

Popcorn diacetyl and bronchiolitits obliterans....are amyloids there?
http://www.ncbi.nlm.nih.gov/pubmed/12151470
http://www.ncbi.nlm.nih.gov/pubmed/17541015
http://www.ncbi.nlm.nih.gov/pubmed/17464280
http://www.ncbi.nlm.nih.gov/pubmed/18772104
 http://www.livescience.com/22308-new-microwave-popcorn-chemical-linked-to-lung-damage.html

http://www.ncbi.nlm.nih.gov/pubmed?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17541015&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVLinkOut 

Renal amyloid after bronchioltitis ?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004490/

At this point  I am looking at or for evidence that herpes or diacetyl destroys the mitochondria causing amyloid plaques in similar ways.

Here is the link to an older post looking at the overlap of Alzheimer's & Parkinson's
http://angelabiggs.blogspot.com/2013/09/alzheimers-parkinsonstourettes-how-do.html 

Genetic forms of Alzheimer's and mitochondria damage (not herpes or diacetyl but mitochondria is key)
http://www.ncbi.nlm.nih.gov/pubmed/24569455 

Mother's of Downsyndrome children have increased risk of Alzheimer's (more evidence of faulty mitochondrias)
http://www.ncbi.nlm.nih.gov/pubmed/7914304
http://www.ncbi.nlm.nih.gov/pubmed/11571320
http://www.ncbi.nlm.nih.gov/pubmed/10402505

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