Examining liver cancer using the co-carcinogenesis hypothesis

Liver cancer

Francis Peyton Rous' Co-carcinogenesis hypothesis: that a virus and a carcinogen together cause cancer. (1966 nobel prize)

What I surmise from his hypothesis:

A virus enters a cell through a receptor, opens up and alters host DNA telomeres. The carcinogen with a benzene ring inhibits the virus' polymerase because viral polymerases have stronger binding affinities than the host's.

Cancer cells can make unlimited copies because of the telomere modifications. Co-carcinogenesis requires a virus and a carcinogen to start the cancer. The cancer tumor wears the entry receptor on the surface.

alcohol as a carcinogen in liver cancer
http://www.ncbi.nlm.nih.gov/pubmed/23101985

Hepatitis viruses as the triggers: means there should be at least 3 types of liver cancer (hepatomas)

Hepatitis A is an enterovirus
Hepatitis B is a polyomavirus
Hepatitis C is a flavivirus

hepatitis B as a polyomavirus would use serotonin  receptors
http://www.ncbi.nlm.nih.gov/pubmed/23087410

Hepatocellular carcinoma and hepatitis B
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047495/
http://www.medscape.com/viewarticle/709167
http://www.ncbi.nlm.nih.gov/pubmed/19702903

hepatitis C as a flavivirus would use the melanocortin receptors
http://www.meduniwien.ac.at/Hans-und-Blanca-Moser-Stiftung/images/projekt_krenbek.pdf

Hepatitis C and heptoblastoma
http://www.ncbi.nlm.nih.gov/pubmed/19207587

Angiosacrcoma is a liver cancer of the liver's blood vessels

Angiosarcoma has arsenic as the carcinogen.
http://link.springer.com/article/10.1186%2F1471-230X-11-142

hepatitis A as an enterovirus would use the acetylcholine receptors
http://english.sibs.cas.cn/ns/es/201409/t20140930_128798.html

as a cytosolic RNA virus...enteroviruses would not cause cancer.

these receptors are located in the blood vessels of the liver
https://en.wikipedia.org/wiki/Muscarinic_acetylcholine_receptor