Monday, October 28, 2013

Polyarteritis Nodosa and autoimmune cross-targeting? Linked with autoimmune liver disease?

 Hypothesis: The cross-targeting of infections at the same tissue causes autoimmune disease.  One infection marks the outside while another marks the inside...only then does the immune system become confused and attack. A virus marks the inside of the liver while an infections marks the outside.....in this case instead of at the liver it occurs in the blood vessels....maybe starting near the liver?


Polyarteritis nodosa is known to have active Hepatitis B
http://www.ncbi.nlm.nih.gov/pubmed/20605819 
http://www.ncbi.nlm.nih.gov/pubmed/11059878

 Polyarteritis nodosa could be caused by cross-targeting involving e.coli because I have previous linked the dimorphic e.coli of bladder infections to autoimmune hepatitis and celiac disease.

Polyarteritis nodosa connected to bladder infections and autoimmune hepatitis.
http://www.ncbi.nlm.nih.gov/pubmed/21119556
but the infection would have to get to the arteries or make antibodies against them.  

Mycoplasmas infecting most organs over time.  This would mean that polyarteritis may more commonly be linked with lupus?
http://www.ncbi.nlm.nih.gov/pubmed/21763578
http://lup.sagepub.com/content/4/6/494.abstract

Because mycoplasmas and e.coli infect the bloodstream...it makes sense how this once started could occur all over. 







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