Berger's disease and cross-targeting autoimmunity (NOT Buerger's)

Berger's disease is an autoimmune disease of the Kidney

Hypothesis: The cross-targeting of infections at the same tissue causes autoimmune disease.  One infection marks the outside while another marks the inside...only then does the immune system become confused and attack. A virus marks the inside of the kidney while an infection marks the outside.

Tonsillitis
http://www.ncbi.nlm.nih.gov/pubmed/16566197

Viruses of the Tonsils that have respiratory infections
RSV Respiratory Syncytial Infection  therefore the most likely culprit

RSV of the Kidney (the virus replicates in the kidney not just the tonsils & lungs) The kidney is the cross-target focus.
http://link.springer.com/article/10.1007%2FBF00862085 

duration of RSV virus secretion (IgM and IgA...IgA lasts around 30 days)
http://www.ncbi.nlm.nih.gov/pubmed/9406652
http://www.ncbi.nlm.nih.gov/pubmed/10830453

boys more likely to have RSV detected
http://www.ncbi.nlm.nih.gov/pubmed/15198187
Note that males are more likely to have Berger's then females.

These diseases are connected: Henoch-Schönlein purpura and Berger
http://www.ncbi.nlm.nih.gov/pubmed/10392263  the emphasis is on IgA antibody levels


Now Looking for the non viral infection:

infections possible...
http://www.ncbi.nlm.nih.gov/pubmed/10392263
Bowel angina...might connect bladder infection e.coli and celiac
Arthritis would connect mycoplasmas

NOTE that the either mycoplasmas or e.coli could be the culprit for cross-targeting with the RSV virus at the kidney.

Gluten (e.coli/celiac)
http://www.ncbi.nlm.nih.gov/pubmed/12046028
http://www.ncbi.nlm.nih.gov/pubmed/1582590
http://www.ncbi.nlm.nih.gov/pubmed/3113643


Antiphospholipids and the kidney (mycoplasmas/lupus)
http://www.uptodate.com/contents/antiphospholipid-syndrome-and-the-kidney
http://www.uptodate.com/contents/antiphospholipid-syndrome-and-the-kidney/abstract/2