Sunday, March 31, 2013

Autoimmune Thyroid disease

I am trying to separate Graves and Hashimoto's.

Graves has TSH receptor antibodies.  Does the enterotoxin of things like Staph and E. coli which could bind the receptor involve this? Can we try to connect bacterial infections to graves as the trigger for the autoimmune graves disease? Bladder infections (e.coli) or eczema (staph) should be higher in graves patients.

Hashimoto's has anti-peroxidases. The thyroid makes peroxides which could be confused with fungal infections like aspergillus and candida because they secrete peroxidases.  Do patients with candida induced diabetes have Hashimoto's not Graves?  Do patients with aspergillus infections have bulb allergies along with Hashimoto's? (aspergillus niger grows on blubs like onions, garlic, tiger lilies)

Added 4/2
I am looking for the viruses that could be infecting and causing the cross-targeting of the immune system.

For Hashimoto's I found this reference http://www.ncbi.nlm.nih.gov/pubmed/22998463 where they see evidence of a virus that could cause the inflammation but it is unclear which one it is.

Any virus that would infect inflaming the thyroid could push the immune system into the autoimmune disease and they may be the same ones for both of these disease since all it needs to do is confirm the target of the immune system which is already looking because of the antibodies which as built up. (at least my hypothesis predicts this)

Further I want to know if the hepatitis viruses will infect the thyroid and replicate there...not just in the liver.  Can someone look even if it is in a pertri dish thyroid? Can these viruses be jumping to another organ?

Another virus under consideration is the Epstien-barr virus.  Does this virus infect the thyroid itself? This virus has been connected to skin cancer...could it cause thyroid cancer? Could it cause Hashimoto's until that point?

Added 8/3/13   High levels of TSH are associated with bipolar (see new posting) where as low TSH seems connected to tics and Obsessive compulsive disorder.

T3 levels when low in Hashimoto's effects the levels of serotonin.  Extremely low levels of serotonin are currently being investigated for suicide.  Hypothyroid disease is also under consideration through T3 as an instigator of suicide.

The thyroid levels of T, T4, and TSH should all be constantly checked in autoimmune thyroid patients.

I hope the CDC consider these ideas and test them. (these are theories not proven)

Hopeful,
Angela Biggs




 

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