Tuesday, October 20, 2015

some polyomaviruses use somatostatin receptors: are glucagonomas triggered by them?

Hypothesis: Cancers wear the receptors used by the viruses that infected them initially triggering the cancer.

Co-carcinogenesis: A virus and and cancer together trigger cancer.

The carcinogen inhibits the polymerases of the virus. The virus opens the DNA and makes it immortal but then can't use it.

do some polymaviruses use somatostatins?

somatostatin receptors:  gastrinomas, vasoactive intestinal polypeptide-secreting tumors, and glucagonomas
http://www.ncbi.nlm.nih.gov/pubmed/16625862

Glucagonomas and necrolytic migratory erythema
http://www.eje-online.org/content/151/5/531.full.pdf

merkel cells and new polyomavirus
http://www.ncbi.nlm.nih.gov/pubmed/23922031

Merkel and somatostatin receptors
http://www.ncbi.nlm.nih.gov/pubmed/24742330

 necrolytic migratory erythema (NME) without glucagonoma associated with hepatitis B.
http://www.ncbi.nlm.nih.gov/pubmed/15701595

Hepatitis B and somatostatin

Hepatitis B is a type of polyomavirus



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