Lung cancer and Co-carcinogenesis

Francis Peyton Rous' Co-carcinogenesis hypothesis: that a virus and a carcinogen together cause cancer. (1966 nobel prize)

What I surmise from his hypothesis:

A virus enters a cell through a receptor, opens up and alters host DNA telomeres. The carcinogen with a benzene ring inhibits the virus' polymerase because viral polymerases have stronger binding affinities than the host's.

Cancer cells can make unlimited copies because of the telomere modifications.

Types of lung cancer (can we match a virus to each type?)

non-small cell carcinoma (85%) there are 3 types:

Squamous cell
adenocarcinoma
Large cell carcinoma


Small cell cancer? oat cell cancer? what virus is connected to this one? EBV?

scleroderma and small cell lung cancer
http://onlinelibrary.wiley.com/doi/10.1002/jso.2930290109/abstract
https://www.ncbi.nlm.nih.gov/pubmed/2841907
https://www.ncbi.nlm.nih.gov/pubmed/15897643

Cannabinoid receptors and non-small cell lung carcinoma?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025486/
http://www.ncbi.nlm.nih.gov/pubmed/21097714

Cannibus reduces tumors in 50% of common lung cancer
https://patients4medicalmarijuana.wordpress.com/marijuana-info/marijuana-and-your-lungs-recent-studies/

Squamous cell and HPV (HPV uses cannabinoid receptors..HPV?)
http://www.oncologynurseadvisor.com/headlines/hpv-infection-lung-cancer-risk/article/378102/

Squamous lung cells moved to breast (HPV also infects the breast)
http://www.ncbi.nlm.nih.gov/pubmed/18505069

Adenocarcinomas and adenosine receptors
http://www.ncbi.nlm.nih.gov/pubmed/23917542

adenoviruses are 10% of lung infections and have been found in adenocarcinomas
http://www.cancerbiomed.org/index.php/cocr/article/view/157

So what virus causes large cell carcinoma? Flaviviruses?

Large cell carcinomas and neuroendocrine tumors
http://journals.lww.com/ajsp/Abstract/1991/06000/Neuroendocrine_Tumors_of_the_Lung_With_Proposed.3.aspx

melanocortin receptors and neuroendocrine cells of brain (until i find a better reference)
http://www.ncbi.nlm.nih.gov/pubmed/7854347

Melanocortin receptors  and lung cancer
http://www.ncbi.nlm.nih.gov/pubmed/22147647
Lewis lung carcinoma
https://en.wikipedia.org/wiki/Lewis_lung_carcinoma

Logically this means some cancers are linked by viruses.
Large cell lung, melanoma, prostate...flaviviruses
Breast, cervical, squamous....HPV