HLA-dr
HLA-dr appears to hold virus RNA
https://www.ncbi.nlm.nih.gov/pubmed/10564819
HLA-dq
HLA-dq appears to hold small antigens like insulin and gliadin
presentation of gluten in HLA-dq2
https://www.jimmunol.org/content/175/1/254
"It is interesting to note that even if the risk for developing CD associated with DQ2.2 is minuscule compared with that of DQ2.5, a recent study revealed that among the small group of DQ2.5- and DQ8-negative CD patients, "
e.coli binds gliadin
https://pdfs.semanticscholar.org/b70f/23916b8f5553baf3a01055725ab9c68add7c.pdf?_ga=2.119014538.2026673398.1566778373-1275520869.1527777598
HLA-dp and type one diabetes
https://link.springer.com/article/10.1007/s10654-004-5176-9
HLA-dq8 holds insulin
https://www.ncbi.nlm.nih.gov/pubmed/11376336
HLA-dp
HLA-dp appears to hold a significant amount of self antigens as well as foreign and is similar to HLA-dq but is not used as often
HLA-dp review
https://www.jimmunol.org/content/184/5/2492
states that it has a lower expression than HLA-dr or HLA-dq and that HLA-dp has few epitopes. HLA-dp is shared by 90% of the population
HLA-dq has been associated with ALL the childhood leukemia (genetic form) ????
http://www.bloodjournal.org/content/120/15/3039.short?sso-checked=true?sso-checked=true
What is the difference between HLA-dq and dp?
might not be relevant:
beryllium binds to HLA-dp
https://www.ncbi.nlm.nih.gov/pubmed/11423174
cobalt binds to HLA-dp
https://www.ncbi.nlm.nih.gov/pubmed/10427976
No comments:
Post a Comment