CD8 cells not found in GC
http://clincancerres.aacrjournals.org/content/23/1/250
IgG3 has very little somatic hypermutation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413556/
FDC follicular dendritic cell
mD myeloid dendritic cell
pD plasmacytoid dendritic cell
Dendritic cells are " pacmans " of the immune system picking up antigens (related to macrophages)
MHC are mailboxes for showing antigens to T cells
The CD4 and CD8 are clips that hold the mailbox while the TCR t cell receptor looks at the antigen.
Note that T cells are educated in the thymus to know inside self antigens. While the B cells and the BCR b cell receptor is educated to know outside self antigens. The BCR is the reason for somatic hypermutation. BCRs are literally worn antibodies. The somatic hypermutation improves the binding and creates a strong binding antibody.
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