The Zika virus looks as if it binds the ACTH receptor.
I have been dividing up the flaviviruses with the melanocortin receptor they could use:
mcr1 Tick borne encephalitis virus/ hepatitis C (Thrombocytopenia due to red blood cells with mcr1)
mcr2 (ACTH receptor) Zika (placenta, developing brain)
mcr3 West nile (kidneys)
mcr3 and mcr1 Japanese encephalitis
mcr4 Yellow fever (liver)/ hepatitis C
mcr5 Dengue (immune system T cells)
Previous posts of Zika and ACTH receptors
http://angelabiggs.blogspot.com/2017/07/zika-malaria-drugs-and-acth-receptor.html
Suramin blocks Zika infection by binding were the virus attaches
https://www.ncbi.nlm.nih.gov/pubmed/28457855
https://www.ncbi.nlm.nih.gov/pubmed/28461070
Suramin binds the ACTH molecule
https://www.ncbi.nlm.nih.gov/pubmed/2152879
So is suramin binding the virus as if it is an ACTH molecule? Does this support the hypothesis that Zika uses ACTH receptors?
note that suramin is a drug that kills parasites and is used against the sleeping sickness and has been found to find to do other actions....but here with Zika it interferes with viral attachment
Previous post linking virus families to receptor families
http://angelabiggs.blogspot.com/2017/06/updated-virus-families-bind-and-enter.html
I have been dividing up the flaviviruses with the melanocortin receptor they could use:
mcr1 Tick borne encephalitis virus/ hepatitis C (Thrombocytopenia due to red blood cells with mcr1)
mcr2 (ACTH receptor) Zika (placenta, developing brain)
mcr3 West nile (kidneys)
mcr3 and mcr1 Japanese encephalitis
mcr4 Yellow fever (liver)/ hepatitis C
mcr5 Dengue (immune system T cells)
Previous posts of Zika and ACTH receptors
http://angelabiggs.blogspot.com/2017/07/zika-malaria-drugs-and-acth-receptor.html
Suramin blocks Zika infection by binding were the virus attaches
https://www.ncbi.nlm.nih.gov/pubmed/28457855
https://www.ncbi.nlm.nih.gov/pubmed/28461070
Suramin binds the ACTH molecule
https://www.ncbi.nlm.nih.gov/pubmed/2152879
So is suramin binding the virus as if it is an ACTH molecule? Does this support the hypothesis that Zika uses ACTH receptors?
note that suramin is a drug that kills parasites and is used against the sleeping sickness and has been found to find to do other actions....but here with Zika it interferes with viral attachment
Previous post linking virus families to receptor families
http://angelabiggs.blogspot.com/2017/06/updated-virus-families-bind-and-enter.html
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