Sunday, May 7, 2017

Cannabinoid 2 receptors, prostate cancer, breast cancer, HPV18, and olive oil????

I am currently collecting papers of overlap but a pattern seems to be emerging with Cannabinoid 2 receptors in the center.  It is unclear which HPV uses which cannabinoid receptor.

HPV16 for squamous and HPV18 for adenocarcinoma (basal cell)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361088/

cannabinoid 2 receptor regulation of prostate cancer
http://grantome.com/grant/NIH/U54-CA156735-02-5707

olive oil and CB2 receptor
http://content.iospress.com/articles/nutrition-and-healthy-aging/nha160008

Olive oil, prostate cancer and survival
http://www.npr.org/sections/thesalt/2013/06/10/190360777/hey-fellas-olive-oil-and-nuts-tied-to-prostate-cancer-survival

Olive oil and breast cancer risk
http://www.health.harvard.edu/womens-health/research-were-watching-high-olive-oil-consumption-linked-to-lower-breast-cancer-risk

cannabis THC binds the CB1 receptor (the nerve slowing reaction)  and the CB2 receptor which might be the reason for the munchies?

CB2 receptors are increased in breast cancer
https://www.ncbi.nlm.nih.gov/pubmed/27213582

but Squamous breast cancer is rare???
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931217/

what is the difference between the round and the squamous triple negative cancers?

HPV and breast cancer ?
https://infectagentscancer.biomedcentral.com/articles/10.1186/s13027-016-0058-9
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172760

HPV and actinic keratosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642014/

Basal cell carcinoma and actinic keratosis have increased phospholipids
https://www.ncbi.nlm.nih.gov/pubmed/10397583

CB1 receptor and CB2 receptor antagonists increase lipids in liver (fatty liver )
https://www.ncbi.nlm.nih.gov/pubmed/20602678

Clear cell carcinoma has lipid metabolism issues causing the yellow look of the cells

Clear cell: is this HPV18 and CB1? 

Clear cell renal cell carcinoma and HPV

HPV and renal cell carcinoma
http://onlinelibrary.wiley.com/doi/10.1002/jmv.23945/abstract

clear cell penis carcinoma is squamous HPV
http://journals.lww.com/ajsp/Citation/2016/07000/Clear_Cell_Carcinoma_of_the_Penis___An_HPV_related.6.aspx

HPV does demethylation

Clear cell renal cell carcinoma and herv E
https://www.ncbi.nlm.nih.gov/pubmed/26862115

Clear cell cancer and cannabinoid receptors of the CB1 type are decreased? and CB2 is not expressed?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989249/

Here they found over expression of CB1: but they are not specific which kind of RCC
https://www.springermedizin.de/overexpression-of-cannabinoid-receptor-1-promotes-renal-cell-car/10898958

clear cell renal carcinoma actually have a golden yellow appears due to an accumulation of lipids
http://emedicine.medscape.com/article/1612043-overview?pa=58O8ipQc5%2Buu2M08DeBeRLaqlzPm8CfcZzRXra9ztt%2BlokvVNZ%2FAwbhQ5uyMd8txHhCnHvXnShVL70%2Fs9Tn3YrOwhd8Mdk7tVO%2FdkscsGC4%3D

clear cell renal carcinoma seem to lipid issues connect to ceramide levels
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172632

CB1 cannabinoid receptor one is connected to ceramide
https://www.ncbi.nlm.nih.gov/pubmed/15958274

note that clear cell carcinoma of the cervix is hpv18 
http://journals.lww.com/intjgynpathology/Abstract/2012/05000/Clear_Cell_Adenosquamous_Carcinoma_of_the_Cervix__.15.aspx

Papillary thyroid cancer into clear cell renal cancer
https://www.ncbi.nlm.nih.gov/pubmed/28249616

HPV16 and thyroid cancer
https://www.ncbi.nlm.nih.gov/pubmed/18985036

Clear cell of the head and neck connected to metastatic renal cell
http://www.sciencedirect.com/science/article/pii/S1741940904000172

Head and neck cancer with HPV16?
https://www.ncbi.nlm.nih.gov/pubmed/24474236






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