Pondering TNF alpha

How do mycobacterias increase the THF alpha?

Adding TNF alpha decreased mycobacteria?
https://www.ncbi.nlm.nih.gov/pubmed/10211990

Is this because the mycobacteria are "hiders" moving into macrophages and embedding into white adipose tissue? The macrophages are favoring the Th17 route of hidden pathogens by increasing THF alpha?

Macrophages take up mycobacterias but then the mycobacterias survive inside the macrophage?
https://www.ncbi.nlm.nih.gov/pubmed/11358719

Looking at the diseases I have linked to mycobacterias they all appear to have increased TNF alpha

THF alpha and parkinson's
https://www.ncbi.nlm.nih.gov/pubmed/8015728

THF alpha and multiple sclerosis
http://www.medscape.com/viewarticle/583080_9

TNF alpha and psoriasis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924720/

TNF alpha and type 2 diabetes
https://www.ncbi.nlm.nih.gov/pubmed/12532159/
http://www.nature.com/ijo/journal/v27/n1/full/0802187a.html

Increased TNF alpha has also been linked to IBD and major depression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229361/
those on anti-TNF for the IBD developed depression

TNF alpha blockers have been shown to worsen TB. Use of blockers made the illness worse. Is this because the macrophages are hiding?

Hypothesis: Macrophages release TNF at high rates when they themselves have become infected by mycobacterias or viruses

TNF and viruses
https://www.ncbi.nlm.nih.gov/pubmed/8832967

Sendai virus infecting macrophages
https://www.ncbi.nlm.nih.gov/pubmed/168154

flu viruses and macrophages
http://www.futuremedicine.com/doi/pdf/10.2217/fvl.14.65
https://www.ncbi.nlm.nih.gov/pubmed/22894921
https://www.ncbi.nlm.nih.gov/pubmed/26423941

RA patients taking TNF blockers develop something that looks like psoriasis

High TNF alpha also seems to be involved in skin tumors.

HPV which uses cannabinoid receptors causes tumors.

Cannabinoid receptors can cause an increase in TNF alpha
https://www.ncbi.nlm.nih.gov/pubmed/19047095 (is this the same for skin cells?)

Green tea's EGCG seems to inhibit mycobacteria growth. How does that work?

Green tea's ECGC inhibits mycobacteria cell growth
https://www.ncbi.nlm.nih.gov/pubmed/25495515

Green tea attacks the mycobacteria that are inside macrophages
https://www.ncbi.nlm.nih.gov/pubmed/16352457

Further EGCG would help nerve growth....Less TNF alpha and more nerve growth factor.

Nerve growth factor/ TNF alpha receptors are on nerve endings and these receptors are in the same "family" of receptors