Tuesday, September 22, 2015

Hypothesis Co-carcinogenesis: a virus and a carcinogen together cause cancer.

Francis Peyton Rous
Proved that viruses, specifically the HPV, were involved in tumors and that they could become cancer in 1911
He received the  nobel in 1966
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647430/

Co-carcinogenesis
This Cancer potentiation hypothesis was called Co-carcinogenesis
http://www.nature.com/onc/journal/v23/n38/full/1207822a.html

Herpes virus simplex 2 and Benzene together transformed regular cells into cancer 1982 paper
http://www.ncbi.nlm.nih.gov/pubmed/6293737

What is the Current support?

Viruses stabilize the telomeres and allow for unlimited copies
http://www.cell.com/cell-reports/pdf/S2211-1247(14)00973-5.pdf

Benzene blocks polymerases
http://www.ncbi.nlm.nih.gov/pubmed/2926830

Viruses have their own polymerases. Are the wrong polymerases inhibited thus releasing our own into unlimited copies?

Can we match cancers and viruses up?

1 comment: