Monday, September 21, 2015

Carcinogens, benzenes, cancer and polymerases

Hypothesis Co-carcinogenesis: a virus and a carcinogen together cause cancer.

Benzene may inhibit DNA synthesis through polymerases
http://www.ncbi.nlm.nih.gov/pubmed/2926830

Viruses have their own polymerases. Viruses open up the DNA cookbook and bind up the telomeres for unlimited copies. Does this prime the cells for a carcinogen? We should bring back the co-carcinogenesis theory of the 1980s where a virus and a carcinogen together causing cancer.

How many of these carcinogens will function like Benzene?

cig smoke: Benzoapyrene
https://en.wikipedia.org/wiki/Benzo(a)pyrene

Benzene aromatic, hydrocarbon from crud oil
https://en.wikipedia.org/wiki/Benzene

??? oxybenzone ??? the main ingredient in sunscreen is not?
https://en.wikipedia.org/wiki/Oxybenzone

Aflatoxin (peanut mold's toxin is aflatoxin)
https://en.wikipedia.org/wiki/Aflatoxin

Aflatoxin vs Benzene
http://chemistry.stackexchange.com/questions/4168/aflatoxin-versus-benzene-permissible-levels

equilenin
https://en.wikipedia.org/wiki/Equilenin

equilenin and cancer
http://www.ncbi.nlm.nih.gov/pubmed/25611945

doesn't quite look like estrogen because it has another benzene ring

Estrogen
https://en.wikipedia.org/wiki/Estrogen

benzene,Toulene, and zylene
http://www.ncbi.nlm.nih.gov/pubmed/9651624

Phenol groups and polymerases
http://www.ncbi.nlm.nih.gov/pubmed/12459026

Phenols are disinfectants. How are they killing bacteria? Are phenol based disinfectants stop DNA synthesis? (they are benzene rings with an OH group on them)

phenols and coal tar...Carbolic soap
https://en.wikipedia.org/wiki/Carbolic_soap

Phenols in carmex and chloraseptic spray

Phenols and alcohols are considered organic solvents one can use to stop PCR. Which means inhibiting polymeases.

Pentachlorophenol which is a chemical they use to treat outdoor wood with: fence posts, utility poles and railroad ties.  Also called pcp or angel dust.  Widely used as a fungicide in Chile.

Coal tar is on the carcinogen list.

Oxybenzone was looked at as a possible estrogen substance but as a great sunscreen agent it is in 90% of sunscreens and they claim not carcinogenic.

equilenin causes cancer, benzene causes cancer, coal tar phenols might cause cancer....but oxybenzone which is in our sunscreens doesn't cause cancer?

oh that's right they fed oxybenzone to rats and in such high quantities that people don't believe it causes cancer now.  What if oxybenzone only does if a virus is there? where it could inhibit the wrong polymerase

Note I haven't stopped using sunscreen. I live outdoors.  I know that sunburns can cause cancer but maybe they should check at least in a petri dish oxybenzone and westnile like viruses. They should look at removed melanomas for these flaviviruses ( not the HPV which is in the non-melamona type skin cancer). Maybe what we need is mosquito repelling stuff with the sunscreen.

most melanoma skin cancer is still probably triggered by the sun
http://www.ncbi.nlm.nih.gov/pubmed/76759/

Note that UV can release nitrite stores in the skin
http://www.nature.com/jid/journal/v134/n7/full/jid201427a.html
http://www.ncbi.nlm.nih.gov/pubmed/16544952






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