type one diabetes and cross-targeting autoimmunity update

Type one diabetes and the infections of the pancreas. What are the cross-targeting culprits? Does one infection cross-targeted with a virus in the pancreas trigger the autoimmune disease? Like Candida and the flu?

Eisenbarth's Autoimmune Polyendocrine Syndrome Type 1 (APS-I)

Candida
http://www.ucdenver.edu/academics/colleges/medicalschool/centers/BarbaraDavis/Documents/book-Type1DiabetesHTML/type1_ch8.html

Candida infects the pancreas
http://www.ncbi.nlm.nih.gov/pubmed/7944045


Eisenbarth's APS-2 could be bacterial infections  of the pancreas

E.coli infects the pancreas directly
http://gut.bmj.com/content/35/9/1306.full.pdf 

e.coli in the guts of Type 1 diabetes patients
http://www.ncbi.nlm.nih.gov/pubmed/24475780 

History of bladder infections in celiac patients
http://www.ncbi.nlm.nih.gov/pubmed/22185967
note that e.coli often causes bladder infections...so does e.coli have the ability to generate anti-insulin or does it infect the pancreas directly?

Mycoplasmas from Lupus/rheumatoid arthritis infects the pancreas directly
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1412106/

But the autoimmunity does not develop until cross-targeting occurs with a virus
Now for the Viruses:
The flu virus replicates in the pancreas and so does the coxsackie virus.

coxsackie
http://www.ncbi.nlm.nih.gov/pubmed/9257948

flu
http://www.everydayhealth.com/cold-and-flu/1105/flu-virus-may-trigger-diabetes.aspx
http://www.ima.org.il/FilesUpload/IMAJ/0/40/20206.pdf


Interesting 2013 article that supports the celiac and Ecoli connection:
http://www.nytimes.com/2013/02/24/opinion/sunday/what-really-causes-celiac-disease.html?smid=fb-share

One of my 2012 posts:
http://angelabiggs.blogspot.com/2012/10/blog-post.html