There are cytosol receptors that bind infections and then alert the immune system through secreting IFNbeta . Nod1 and nod2 bind bacterial/parasitic infections of the cytosol while rig-1and mda5 bind viruses of the cytosol.
Cytosol bacteria or parasites:
Nod2 and IFNbeta
https://www.frontiersin.org/articles/10.3389/fimmu.2016.00652/full
Nod1 and IFNalpha ?
Nod1 and th17
https://www.sciencedirect.com/science/article/pii/S1074761307002129
Nod1 and Rip-2
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(14)00135-8
does nod1 and nod2 both use Rip-2?
Rip-2 and Th17
http://grantome.com/grant/NIH/R01-AI117968-03
nod 2 and t.gondii
https://www.ncbi.nlm.nih.gov/pubmed/19881508
nod2 and mycobacteria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438743/
https://www.ncbi.nlm.nih.gov/pubmed/25483349
https://www.karger.com/Article/PDF/341472
nod1 and listeria
https://iai.asm.org/content/77/7/2908
nod1 and campylobacteria
https://www.ncbi.nlm.nih.gov/pubmed/17521327
nod1 and inflammasome
http://www.jimmunol.org/content/193/9/4548
Cytosol viruses:
rig-1 and mda5 and IFNbeta
https://www.ncbi.nlm.nih.gov/pubmed/29102119
rig-1 and MDA5 (viral cytosol receptors)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107945/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177755/
inflammasome and rig-1
https://www.cell.com/trends/microbiology/pdf/S0966-842X(14)00198-X.pdf
rig-1 and MDA5 triggered by different types of cytosol viruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224404/
mda5 flu
https://www.ncbi.nlm.nih.gov/pubmed/26074083
An infected cell secretes ifnbeta which sets in motion the pathways for cytosol immune system . The immune system then determines which type of cytosol infection it is dealing with.
Eosinophils and ifn beta
https://www.frontiersin.org/articles/10.3389/fimmu.2018.02330/full
ifn beta induces il-12 from macrophages
https://www.ncbi.nlm.nih.gov/pubmed/9781808
ifn beta induces b7-H1
https://www.ncbi.nlm.nih.gov/pubmed/15342209
ifn-beta il-12 causes TH1 producing ifn gamma
https://www.ncbi.nlm.nih.gov/pubmed/14607924
Cytosol bacteria or parasites:
Nod2 and IFNbeta
https://www.frontiersin.org/articles/10.3389/fimmu.2016.00652/full
Nod1 and IFNalpha ?
Nod1 and th17
https://www.sciencedirect.com/science/article/pii/S1074761307002129
Nod1 and Rip-2
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(14)00135-8
does nod1 and nod2 both use Rip-2?
Rip-2 and Th17
http://grantome.com/grant/NIH/R01-AI117968-03
nod 2 and t.gondii
https://www.ncbi.nlm.nih.gov/pubmed/19881508
nod2 and mycobacteria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438743/
https://www.ncbi.nlm.nih.gov/pubmed/25483349
https://www.karger.com/Article/PDF/341472
nod1 and listeria
https://iai.asm.org/content/77/7/2908
nod1 and campylobacteria
https://www.ncbi.nlm.nih.gov/pubmed/17521327
nod1 and inflammasome
http://www.jimmunol.org/content/193/9/4548
Cytosol viruses:
rig-1 and mda5 and IFNbeta
https://www.ncbi.nlm.nih.gov/pubmed/29102119
rig-1 and MDA5 (viral cytosol receptors)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107945/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177755/
inflammasome and rig-1
https://www.cell.com/trends/microbiology/pdf/S0966-842X(14)00198-X.pdf
rig-1 and MDA5 triggered by different types of cytosol viruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224404/
mda5 flu
https://www.ncbi.nlm.nih.gov/pubmed/26074083
An infected cell secretes ifnbeta which sets in motion the pathways for cytosol immune system . The immune system then determines which type of cytosol infection it is dealing with.
Eosinophils and ifn beta
https://www.frontiersin.org/articles/10.3389/fimmu.2018.02330/full
ifn beta induces il-12 from macrophages
https://www.ncbi.nlm.nih.gov/pubmed/9781808
ifn beta induces b7-H1
https://www.ncbi.nlm.nih.gov/pubmed/15342209
ifn-beta il-12 causes TH1 producing ifn gamma
https://www.ncbi.nlm.nih.gov/pubmed/14607924
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