Hypotheses: Autoimmune Cross-targeting, Co-carcinogenesis, and Quorum complications : Buerger's disease ( thromboangiitis obliterans)...can it be caused by autoimmune cross-targeting?

Tuesday, November 25, 2014

Not to be confused with Berger's disease (IgA nephropathy)

Buerger's disease or thromboangiitis obliterans is an autoimmune disease of the vascular system.
http://www.ncbi.nlm.nih.gov/pubmed/2808505
http://www.ncbi.nlm.nih.gov/pubmed/6392910

Hypothesis: The cross-targeting of infections at the same tissue causes autoimmune disease. One infection marks the outside while another marks the inside...only then does the immune system become confused and attack. A virus marks the inside of the vascular cells while an infection marks the outside.

Is it Rickettsia?
http://www.ncbi.nlm.nih.gov/pubmed/21803838
http://www.ncbi.nlm.nih.gov/pubmed/6897655
http://www.ncbi.nlm.nih.gov/pubmed/6893791

Rocky mountain spotted fever, rickettsia, and kidney failure
http://www.ncbi.nlm.nih.gov/pubmed/434998
http://www.ncbi.nlm.nih.gov/pubmed/1996579
http://www.ncbi.nlm.nih.gov/pubmed/9003109

Gangrene and Rocky mountain spotted fever
http://www.ncbi.nlm.nih.gov/pubmed/8507753
http://www.ncbi.nlm.nih.gov/pubmed/7748070

IMPORTANT: Tobacco use can cause antibodies which may mean this is the first autoimmune disease that may not require 2 infections for cross-targeting to occur!!!
http://www.ncbi.nlm.nih.gov/pubmed/1598672
http://www.ncbi.nlm.nih.gov/pubmed/6426348

smokeless tobacco extract changes vascular cells
http://www.ncbi.nlm.nih.gov/pubmed/10708806

So the parasite would make the outside and the tobacco chemical would mark the inside?

Here is a Virus triggering the Buerger's: Coxsackie virus

Buerger's overlaps with takayasu and juvenile arthritis