Tuesday, September 24, 2013

Dermatitis Herpetiformis, Celiac, and E.coli ...caused by cross-targeting autoimmunity?

Autoimmune Hypothesis:
Cross-targeting of the immune system by a viral infection marking the inside of a host cell and second infection marking the outside of the host cell causes autoimmune disease where the organ is attacked.  In the case of Celiac disease: Antibodies against e.coli mark the outside of the intestine then an intestinal virus (mono or hepatitis) infection marks the inside of the intestinal cells.

If celiac disease is e.coli then what about Dermatitis Herpetitformis?

Dermatitis Herpetiformis has been correlated with Celiac.  25% of patients with Celiac disease have  HD.
http://celiac.nih.gov/Dermatitis.aspx

D. herpitiformis and  thesmall intestine's bacteria
http://www.ncbi.nlm.nih.gov/pubmed/4210511

E.coli causes small intestine infections
http://www.pathologyoutlines.com/topic/smallbowelEcoli.html

 The e.coli of bladder infections is the same e.coli of skin infections
http://jcm.asm.org/content/47/6/1811

 Bladder Infections and celiac disease in children
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1511510/

Celiac viral infections: hepatitis and adenoviruses (mono)
http://www.sciencedirect.com/science/article/pii/S1568997208002012
http://www.ncbi.nlm.nih.gov/pubmed/25212692
http://www.ncbi.nlm.nih.gov/pubmed/15492610
http://www.ncbi.nlm.nih.gov/pubmed/23982094

Celiac disease found in hepatitis patients
http://www.ncbi.nlm.nih.gov/pubmed/15645466

This page is still under construction...See previous post of mine: Celiac disease as an autoimmune disease where e.coli is connected to gluten through dimorphic switching.

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