Viruses use receptors to gain access to host cells. Looking at the autoimmune diseases triggered by the avian flu: parkinson's, diabetes, autism of the frontal lobe I realized that they were all dopamine organs.
The dopamine 2 receptor is on the pancreas
http://www.jbc.org/content/280/44/36824.full
D2 and the substantia nigra
http://www.ncbi.nlm.nih.gov/pubmed/1825842
http://www.hindawi.com/journals/ijmc/2011/403039/
Frontal lobe and D2
http://www.sciencedirect.com/science/article/pii/S1053811906011049
The flu virus and parkinson's
http://news.sciencemag.org/brain-behavior/2009/08/bird-flu-virus-possible-trigger-parkinsons
Could it be that the flu uses the D2 receptor to infect cells?
The receptor that people have found them using is hemaggluten. Hemaggluten is the antigen on red blood cells that we use to identify blood types. This had me puzzled.
However the dopamine D2 receptors have a hemogglutin epitope. ( a matching piece)
http://www.jbc.org/content/274/28/19894.abstract
If we know which organs viruses can infect we can predict which autoimmune diseases they can trigger.
Autoimmune hypothesis : autoimmunity is triggered by overlapping infections cross-targeting immune attack. A virus infects the inside while a larger infection marks the outside.
Interesting extras:
humans and birds use of dopamine to create vocalizations
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362661/
Eggs may have a protein that inhibits bird flu virus
http://www.sciencedaily.com/releases/2015/05/150508082629.htm
Note that swine flu might use the similar receptors because it also found in the pancreas
http://www.ima.org.il/FilesUpload/IMAJ/0/40/20206.pdf
Narcolepsy and d2
https://books.google.com/books?id=yTLkszI1to0C&pg=PA65&lpg=PA65&dq=hypothalamus+dopamine+d2+narcolepsy&source=bl&ots=HxMs7elGV8&sig=6AkV7PFe4f1iZGo_pLSel8qLz_8&hl=en&sa=X&ei=5G-FVYX2KcadygTOjp24Dg&ved=0CC0Q6AEwAw#v=onepage&q=hypothalamus%20dopamine%20d2%20narcolepsy&f=false
Swine flu vaccine and narcolepsy...swine flu is also found in the brain in dopamine organs
http://www.newscientist.com/article/dn24772-flu-vaccine-helps-unravel-complex-causes-of-narcolepsy.html#.VYVw0GK9KK0
Flu then narcolepsy
http://www.ncbi.nlm.nih.gov/pubmed/11421428
Is narcolepsy cross-targeting autoimmunity? Did these kids have another infection?
Strep and narcolepsy has been suspected
http://www.aasmnet.org/jcsm/ViewAbstract.aspx?pid=28864
Target in narcolepsy: hypocretin neurons?
http://healthysleep.med.harvard.edu/narcolepsy/what-is-narcolepsy/science-of-narcolepsy
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