Tuesday, June 3, 2014

Autoimmune hemolytic anemia and cross-targeting autoimmunity?

Hypothesis: Cross-targeting autoimmunity occurs when 2 infections, one being a virus, infect the same target and cause the immune system to escalate the immune attack into autoimmunity because both the inside and the outside of the organ/self is marked as infected.

Autoimmune Hemolytic anemia and Mycoplasma pneumoniae
http://www.ncbi.nlm.nih.gov/pubmed/23800801
http://www.ncbi.nlm.nih.gov/pubmed/17330697
http://ispub.com/IJHE/4/1/3542
http://www.hindawi.com/journals/crim/2012/649850/
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000100018
http://njcc.nl/sites/default/files/NJCC_04%20vdHoek.pdf
http://www.ncbi.nlm.nih.gov/pubmed/19578637
http://www.ncbi.nlm.nih.gov/pubmed/8399937

Autoimmune Hemolytic anemia and Hepatitis C
http://www.ncbi.nlm.nih.gov/pubmed/11799634
http://www.ncbi.nlm.nih.gov/pubmed/15297855
http://www.ncbi.nlm.nih.gov/pubmed/24879173
http://www.ncbi.nlm.nih.gov/pubmed/10608148
http://www.ncbi.nlm.nih.gov/pubmed/12886829
http://www.ncbi.nlm.nih.gov/pubmed/15871666
http://www.ncbi.nlm.nih.gov/pubmed/21891998

Autoimmune hemolytic anemia and mono (Epstein-Barr virus)
http://www.ncbi.nlm.nih.gov/pubmed/21891998
http://www.ncbi.nlm.nih.gov/pubmed/7314221

Epstein-barr infects the liver just like hepatitis does and mildly effects the liver's ability to function.

LUPUS (rheumatoid )and hemolytic anemia
http://www.ncbi.nlm.nih.gov/pubmed/10723973
http://www.ncbi.nlm.nih.gov/pubmed/7899874

Rheumatoid, lupus, and mycoplasmas
http://www.ncbi.nlm.nih.gov/pubmed/9550495
http://www.ncbi.nlm.nih.gov/pubmed/4726069
http://www.ncbi.nlm.nih.gov/pubmed/5156883

Note that the west nile virus infects the spleen
http://www.ncbi.nlm.nih.gov/pubmed/24827763

The liver removes toxins but the spleen breaks down the red blood cells
Autoimmunity could also occur here.

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