Hypotheses: Autoimmune Cross-targeting, Co-carcinogenesis, and Quorum complications

Saturday, July 20, 2019

il-27, 25HC, and IgG2a against cytosol viral infections ?

il-27 induces IgG2a from Bcells
https://www.ncbi.nlm.nih.gov/pubmed/15294962

il-27 induces 25hc
https://www.researchgate.net/figure/IL-27-specifically-induces-cholesterol-25-hydroxylase-Ch25h-expression-and-25-OHC_fig1_320017159

https://www.researchgate.net/publication/320017159_IL-27-Induced_Type_1_Regulatory_T-Cells_Produce_Oxysterols_that_Constrain_IL-10_Production

25HC blocks viral entry
https://www.ncbi.nlm.nih.gov/pubmed/25501851

https://www.ncbi.nlm.nih.gov/pubmed?Db=pubmed&Cmd=ShowDetailView&TermToSearch=27086126

Does 25hc help create exosomes which then binds with dendritic cells and SCS lymph cells?

cd169 binds 25HC to capture exosomes
https://www.ncbi.nlm.nih.gov/pubmed/24255917
https://www.ncbi.nlm.nih.gov/pubmed/29425504

Complement and  IgG2a
https://www.jimmunol.org/content/178/1_Supplement/S159.5
https://www.ncbi.nlm.nih.gov/pubmed/6610105

IgG2a and influenza
https://cvi.asm.org/content/13/9/981

IgG2a with viruses and parasites?
https://academic.oup.com/intimm/article/12/2/223/652665

Does 25hc hold viruses on the surface? how would complement work?

Biggs Hypotheses at 7:40 PM
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