Burning mouth syndrome, bells palsy, and silent migraines? Are these connected to herpes?

Bell's palsy could be cross-targeting autoimmunity of herpes with spirochetes.

Herpes viruses use the estrogen receptors to infect cells.  In nerves the beta estrogen receptors cycle to the mitochondria while in other cells the alpha estrogen receptor cycles to the nucleus.

Herpes simplex one and burning mouth syndrome
http://www.ncbi.nlm.nih.gov/pubmed/25833911

Herpes simplex two and burning mouth syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22747939

Bells palsy linked to herpes virus
http://www.nytimes.com/1996/01/03/us/bell-s-palsy-is-linked-with-herpes-infection.html
http://www.lifeextension.com/protocols/neurological/bells-palsy/page-01

Migraine, herpes, facial numbness
http://www.ncbi.nlm.nih.gov/pubmed/20399396
http://www.ncbi.nlm.nih.gov/pubmed/15836587
http://www.ncbi.nlm.nih.gov/pubmed/7402669

Mollaret's and herpes simplex (infection of the protective membranes covering the brain)
http://en.wikipedia.org/wiki/Mollaret%27s_meningitis

migraine and menstrual cycle ( does estrogen cause herpes to emerge?)
http://www.ncbi.nlm.nih.gov/pubmed/25930018

http://www.thehelpernewsletter.org/index.php?option=com_content&view=article&id=190:ask-the-hrc&catid=165:ask-the-experts&Itemid=226

estrogen does appear to reactivate herpes through the estrogen receptor
http://www.ncbi.nlm.nih.gov/pubmed/19846508

Meniere's disease and herpes
http://www.ncbi.nlm.nih.gov/pubmed/12972911

Meniere's disease and vertigo are linked to a virus
http://www.ncbi.nlm.nih.gov/pubmed/19142031
http://www.ncbi.nlm.nih.gov/pubmed/18235200

naming deficit after herpes simplex 1 infection
http://www.ncbi.nlm.nih.gov/pubmed/1565801
http://www.ncbi.nlm.nih.gov/pubmed/6206910
http://www.ncbi.nlm.nih.gov/pubmed/3225585

meniere's in children: vertigo and tinnitus
http://www.ncbi.nlm.nih.gov/pubmed/16623983

asperger's and auditory dyslexia??? Is this caused by CMV or the flu?

strokes and acquired dyslexia alzheimer's. Is herpes zoster involved?
http://www.ncbi.nlm.nih.gov/pubmed/22034787

Herpes zoster and stroke risk have been connected
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902756/
http://cid.oxfordjournals.org/content/early/2014/03/25/cid.ciu098.abstract
http://www.neurology.org/content/82/3/206
http://www.ncbi.nlm.nih.gov/pubmed/25712420

spirochetes and bell's palsy
http://angelabiggs.blogspot.com/2016/05/is-bells-palsy-triggered-by-autoimmune.html

Parkinson's triggers and autoimmune cross-targeting

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.

Looking at chemical triggers and Parkinson's.  Cross-targeting at the substantia nigra could occur not just with a virus like the flu or west nile it could be a chemical marking the inside of the neurons.

west-nile virus infects the substantia nigra
http://www.ncbi.nlm.nih.gov/pubmed/14568817

influenza A and the substantia nigra
http://www.ncbi.nlm.nih.gov/pubmed/11385275
http://www.ncbi.nlm.nih.gov/pubmed/21655265
http://www.ncbi.nlm.nih.gov/pubmed/10507986

Atrazine is absorbed by the substantia nigra and has been connected to parkinson's but how is still unclear. It is a herbicide that can build up in well water.
http://www.mdpi.com/1422-0067/15/2/2811/pdf

Weirdly the mycobacteria eats the atrazine (could be irrelevant )
http://www.ncbi.nlm.nih.gov/pubmed/25603295

Mycoplasmas or norcardia, they are similar, still would have to mark the outside of the substantia nigra neurons to trigger autoimmunity. Further they must be the first infection.
http://www.ncbi.nlm.nih.gov/pubmed/25459140
http://www.ncbi.nlm.nih.gov/pubmed/8420152

Older posts on my blog about parkinson's

Herbs, herpes, and Alzheimer's

If Alzheimer's is a disease of malfunctioning mitochondria and herpes viruses infect and travel down nerves in mitochondrias could the action of lemon balm be explained by hindering herpes?

Lemon balm and alzheimer's
http://www.ncbi.nlm.nih.gov/pubmed/22070157
http://www.ncbi.nlm.nih.gov/pubmed/12810768

lemon balm and memory
http://www.ncbi.nlm.nih.gov/pubmed/12888775

Lemon balm and herpes extract
http://www.ncbi.nlm.nih.gov/pubmed/19023806
http://www.ncbi.nlm.nih.gov/pubmed/22377592
http://www.ncbi.nlm.nih.gov/pubmed/18693101

peppermint and herpes
http://www.ncbi.nlm.nih.gov/pubmed/13678235
http://www.ncbi.nlm.nih.gov/pubmed/21607799
http://www.ncbi.nlm.nih.gov/pubmed/19142040

peppermint oil and alzheimer's
http://jass.neuro.wisc.edu/2012/01/Lab%20603%20Group%205%20The%20Effect%20of%20Peppermint%20on%20Memory%20Performance.pdf

Older post son my website
http://angelabiggs.blogspot.com/2014/02/the-mitochondria-and-amyloidosis.html
http://angelabiggs.blogspot.com/2014/07/alzheimers-mitochondria-damage-from.html

Note that other things can damage the mitochondria other than herpes like diacteyl which is the butter flavoring.

updated Alopecia as an autoimmune disease triggered by cross-targeting.

Hypothesis: autoimmunity is triggered by the cross-targeting of infections. A virus marking the inside of the host's cell and an infection, like a fungus, marks the outside.

Looks like a fungus as the outer large infection because Hashimoto's and Vitiligo this blog linked to fungal infections. Guilt by association. 

alopecia and vitiligo
http://www.ncbi.nlm.nih.gov/pubmed/8168460
http://www.ncbi.nlm.nih.gov/pubmed/24131336
http://www.ncbi.nlm.nih.gov/pubmed/22881476
http://www.ncbi.nlm.nih.gov/pubmed/8170863
http://www.ncbi.nlm.nih.gov/pubmed/24700956
http://www.ncbi.nlm.nih.gov/pubmed/17659001

Hashimoto's, type one diabetes, alopecia
http://www.ncbi.nlm.nih.gov/pubmed/25759758

Hashimoto's, alopecia, and aps3
http://www.ncbi.nlm.nih.gov/pubmed/25759758

The other option is atopic dermatitis which I had liked eczema to staph infections.
http://www.e-ijd.org/article.asp?issn=0019-5154;year=2008;volume=53;issue=2;spage=70;epage=74;aulast=Thomas
This group would not have hashimoto's or vitiligo but instead peanut allergies and/or asthma.

As for the virus marking the inside I am not sure. Flaviviruses or herpes viruses. (maybe either)

Current suspects for the virus inside are varicella or hepatitis C.

varicella zoster and alopecia
http://www.ncbi.nlm.nih.gov/pubmed/23526118

note that when shingles (the zoster virus) triggers alopecia  hair loss this would occur only on one side of the head because of the way the virus spreads through the nerves to the skin
http://www.everydayhealth.com/shingles/scalp-problems.aspx

hepatitis C and alopecia
http://www.ncbi.nlm.nih.gov/pubmed/24558223
http://www.ncbi.nlm.nih.gov/pubmed/23181541

hepatitis C can infect the skin
http://emedicine.medscape.com/article/1134161-clinical

Note that hepatitis is typically associated with the urticaria rash
http://www.alopeciaworld.com/forum/topics/alopecia-autoimmune-urticaria
Here a woman says that those hives appearing matched with the hair growing back but she is not sure how.

alopeica and melanocortin 2 /ACTH receptors...the receptors have decreased in AA?
http://www.ncbi.nlm.nih.gov/pubmed/20590821


Hepatitis C is a flavivirus. Flaviviruses use melanocortin receptors

male baldness and prostate cancer connection?
http://www.ncbi.nlm.nih.gov/pubmed/25225425

african americans have increased risk
http://www.ncbi.nlm.nih.gov/pubmed/23532004

hepatitis C and prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/21557839

i am not saying that men with male baldness have hepatitis just that there must be an increase in the receptors??? or something

do the different flaviviruses have different binding affinities for the melanocortin receptors?
west nile stronger for MCR 1 (red heads seem to have a variant of this and have more skin cancer)
hepatitis stronger for MCR 2???

vitiligo, lupus and Trichophyton violaceum
http://www.ncbi.nlm.nih.gov/pubmed/11036404

http://www.idoj.in/article.asp?issn=2229-5178;year=2015;volume=6;issue=7;spage=60;epage=63;aulast=Rao

could this be the fungus of vitiligo?

Images of Red blood cells and infections
http://www.bloodcytology.com/blood-images/

specifically talks about fungal infections and low B12 


low B12 can cause pernicious anemia


Pernicious anemia and alopecia
http://www.ncbi.nlm.nih.gov/pubmed/18614380

Vitiligo and pernicious anemia
http://www.nejm.org/doi/full/10.1056/NEJMicm990602

Nickel allergy, Hashimoto's, endometriosis and vitiligo are they fungal infection triggered?

Looking at nickel allergy it overlaps with the fungal associated group of autoimmune diseases. Could nickel allergy be an indication of some kind of fungal infection?

Nickel and Saccharomyces
http://www.ncbi.nlm.nih.gov/pubmed/10438744
http://www.ncbi.nlm.nih.gov/pubmed/9231423

High rate of nickel allergy and Endometriosis
http://www.ncbi.nlm.nih.gov/pubmed/25976177

allergies and Endometriosis
http://www.ncbi.nlm.nih.gov/pubmed/22369407

Endometriosis is associated with Hashimoto's thyroid disease which previously on this blog was linked to fungal infections.

Hypothyroid and Endometriosis
http://www.ncbi.nlm.nih.gov/pubmed/17720700

Hashimoto's and Endometriosis
http://www.readcube.com/articles/10.4172/2167-7948.1000134

Endometriosis in horses has been associated with candida

http://www.ncbi.nlm.nih.gov/pubmed/23270362

Contact vitiligo with nickel

http://www.ncbi.nlm.nih.gov/pubmed/11300099

http://www.ncbi.nlm.nih.gov/pubmed/1877258

?http://www.natureandhealth.com.au/news/vitiligo-what-your-doctor-doesn-t-know?

Vitiligo and candida

http://www.ncbi.nlm.nih.gov/pubmed/23252470

vitiligo and Hashimoto's

http://www.ncbi.nlm.nih.gov/pubmed/25615429

To remove nickel yeast can be used which means fungus binds nickel really well
http://www.ncbi.nlm.nih.gov/pubmed/20452730
http://www.ncbi.nlm.nih.gov/pubmed/19245404

How nickel is toxic:
http://www.ncbi.nlm.nih.gov/pubmed/19917080

Idiopathic pericarditis is it caused by autoimmune cross-targeting?

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.


Idiopathic pericarditis could be a fungus marking the outside with a virus like coxsackie or echo-virus  marking the inside of the myocyte.

Sjogren's and Pericarditis (fungus)
http://www.ncbi.nlm.nih.gov/pubmed/17435839

Hashimoto's and pericarditis (fungus)
http://www.ncbi.nlm.nih.gov/pubmed/25791974

Colchicine and pericarditis where the drug appears to make an impact
http://www.ncbi.nlm.nih.gov/pubmed/16186437

Colchicine is a microtubule inhibitor
http://www.febsletters.org/article/S0014-5793(07)01029-0/abstract

Tuberculous pericarditis (could replace the fungus marking the outside)
http://www.ncbi.nlm.nih.gov/pubmed/8170726

Viruses and pericarditis
http://www.ncbi.nlm.nih.gov/pubmed/18708165 (coxsacke or echo-virus)
http://www.ncbi.nlm.nih.gov/pubmed/25760570 (epstein-barr)
http://circ.ahajournals.org/content/119/19/2615.full.html (review of heart viruses)

idopathic achalasia as an autoimmune disease triggered by cross-targeting

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.

idiopathic achalasia has been connected with autoimmune disease
http://www.sciencedaily.com/releases/2014/07/140729073644.htm
http://www.ncbi.nlm.nih.gov/pubmed/15929777
It may or may not be autoimmune itself

the virus could be varicella zoster
http://www.ncbi.nlm.nih.gov/pubmed/8386130
or herpes
http://www.ncbi.nlm.nih.gov/pubmed/23973923

idiopathic achalasia could be triggered by a throat infection
like h.pylori as the large infection
http://www.ncbi.nlm.nih.gov/pubmed/15325006

I think another choice is Candida/ fungal infections for the "outer" infection

Very high rate of  uveitis with achalasia
uveitis which is swelling of the middle layer or region of the eye
http://www.ncbi.nlm.nih.gov/pubmed/21899655

what are the types of uveitis
http://www.merckmanuals.com/professional/eye-disorders/uveitis-and-related-disorders/overview-of-uveitis

vitiligo and uveitis
http://www.ncbi.nlm.nih.gov/pubmed/7195407
http://www.ncbi.nlm.nih.gov/pubmed/6869476

vitiligo and candida antigens
http://www.ncbi.nlm.nih.gov/pubmed/23252470

uveitis and candida
http://www.ncbi.nlm.nih.gov/pubmed/25870216

Hashimoto's and achalasia patterns indicate that maybe 1/4 of cases are fungal
http://www.wjgnet.com/1007-9327/13/594.pdf
http://www.ncbi.nlm.nih.gov/pubmed/23329193
http://www.ncbi.nlm.nih.gov/pubmed/17278227
http://www.ncbi.nlm.nih.gov/pubmed/21899655




chagas which is caused by t.cruzi can cause achalasia
http://en.wikipedia.org/wiki/Chagas_disease

comparing chagas to idiopathic achalasia (they are different)
http://www.ncbi.nlm.nih.gov/pubmed/20545981

Chemically induced autoimmunity

Chemically induced autoimmunity could occur through cross-targeting autoimmunity

Chloroetheylene induces autoimmunity
http://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.abstractDetail/abstract/875

Chloroetheylenes are absorbed by the nerves and muscles
http://en.wikipedia.org/wiki/Trichloroethylene


In addition to the immediate chemical reactions causing illness, if a patient has a preexisting infection marking the outside of any of these cells which absorb the chloroetheylene they could have autoimmunity triggered. Chemicals absorbed into cells would be marked as containing foreign material just as if infected by a virus.

Autoimmune cross-targeting hypothesis: a virus marks the inside of a cell while a larger infection marks the outside and the combination triggers autoimmune disease.  The immune system is instructed to destroy both the inside and the outside of the target.

If a patient had RA mycoplasmas they could have the joints attacked.  If the patient had liver disease with anti-muscle antibodies then lupus could be triggered.  If the patient merely had psoriasis or eczema then multiple sclerosis could be triggered.  The key pattern here is that the outside and the inside of a target tissue is marked for autoimmune disease to be triggered.